PSOC@Penn Seminar: Keshav Patil
PSOC@Penn Seminar: Keshav Patil
Physical Sciences in Oncology Center PSOC@Penn Spring 2022 Hybrid-Seminar Series Towne 225 / Raisler Lounge @ Noon (EST) For Zoom link , please contact manu@seas.upenn.edu
Physical Sciences in Oncology Center PSOC@Penn Spring 2022 Hybrid-Seminar Series Towne 225 / Raisler Lounge @ Noon (EST) For Zoom link , please contact manu@seas.upenn.edu
Inspiration from animal function can lead to effective design of engineered systems. Ocean systems benefit especially as operation in a heavy medium such as water imparts significant forces. We provide two examples of biomimetic design. In the first example, morphing fins inspired from tunas are used to dynamically change the directional stability qualities of rigid […]
Learning how to create, study, and manipulate highly entangled states of matter is key to understanding exotic phenomena in condensed matter and high energy physics, as well as to the development of useful quantum computers. In this talk, I will discuss recent experiments where we demonstrated the realization of a quantum spin liquid phase using […]
Vaccines prevent 4-5 million deaths a year making them the principal tool of medical intervention worldwide. Nucleoside-modified mRNA was developed over 15 years ago and has become the darling of the COVID-19 pandemic with the first 2 FDA approved vaccines based on it. These vaccines show greater than 90% efficacy and outstanding safety in clinical […]
A photonic-electronic system can potentially process enormous amounts of data that no stand-alone electronics have been capable of. Furthermore, a chip-scale optical atomic clock can be so precise that it only loses the equivalent of one second every million years. In the foreseeable future, highly integrated photonics can usher disruptive advances in communications, deep learning, […]
*This will be a HYBRID Event with in-person attendance in Levine 512 and Virtual attendance via Zoom Balancing performance and safety are crucial to deploying autonomous vehicles in multi-agent environments. In particular, autonomous racing is a domain that penalizes safe but conservative policies, highlighting the need for robust, adaptive strategies. Current approaches either make simplifying assumptions […]
Abstract Our group is broadly focused on understanding and controlling the intersection of biology and materials at the molecular level. This intersection is critical in many areas of biotechnology where proteins and enzymes are integrated into or in constant contact with materials, including biocatalysis, tissue engineering, drug delivery, biosensing, and vaccine formulation. In line with […]
Many-body quantum systems are the most powerful computers allowed by Nature. How do they work? Can we control them? Are they useful? In this talk, I discuss how recent results in quantum information theory translate into quantum engineering solutions. I introduce a geometric information measure that rigorously evaluates the difference between two complex configurations of arbitrarily […]
This talk will on be on zoom
https://upenn.zoom.us/j/92928358554?pwd=MWdDU0lJRmE3U0hDWUdmU284UmNGZz09
Meeting ID: 929 2835 8554
Passcode: 488035
This seminar will be held in person and via zoom - check email for link. The properties of the microenvironment in which cells reside, from structure to mechanics and biochemical content, increasingly are recognized as important drivers of cell function and fate, including in the onset and progression of disease (e.g., late cancer recurrence and […]
*This seminar will be held in-person in Wu and Chen Auditorium as well as virtually via Zoom. Research at the Center for Robotics and Biosystems at Northwestern University encompasses bio-inspiration, neuromechanics, human-machine systems, and swarm robotics, among other topics. In this talk I will give an overview of some of our recent work, with a particular […]
Fiber networks at different length scales represent a prevalent microstructure of highly deformable materials and biological matter. At the microscale, these fiber networks are key for the function of biological systems, while at the macroscale they endow materials with striking characteristics, such as unusual kinematic behavior and high defect tolerance. Resolving the microstructure in discrete […]
This seminar will be held virtually via Zoom. Robotic grasping and manipulation has historically been dominated by rigid grippers, force/form closure constraints, and extensive grasp trajectory planning. The advent of soft robotics offers new avenues to diverge from this paradigm by using strategic compliance to passively conform to grasped objects in the absence of active control, and with […]
Physical Sciences in Oncology Center PSOC@Penn Spring 2022 Hybrid-Seminar Series Towne 225 / Raisler Lounge @ Noon (EST) For Zoom link , please contact manu@seas.upenn.edu
Regular building blocks of controlled shape and size can be assembled to create fully dense “architectured” materials and structures. When the building blocks are very stiff and when they interact through much softer materials or even only by frictional contact, the blocks can slide, rotate, separate or interlock collectively, providing a wealth of tunable mechanisms, […]
As two basic properties of light, wavelength and timescale are central to numerous photonic applications. Compared to visible and near-infrared, the longer wavelength mid-infrared spectral regime contains unique thermal visual information and chemical fingerprints of the environment. On a different front, femtosecond light sources and systems can enable ultrafast information processing, sensing, and computing. Yet, […]
Uncertainty quantification is a recent emerging interdisciplinary area that leverages the power of statistical methods, machine learning models, numerical methods and data-driven approach to provide reliable inference for quantities of interest in natural science and engineering problems. In practice, the sources of uncertainty come from different aspects such as: aleatoric uncertainty where the uncertainty comes […]
*This will be a HYBRID Event with in-person attendance in Levine 512 and Virtual attendance via Zoom Offline reinforcement learning (RL), which uses pre-collected, reusable offline data without further environment interactions, permits sample-efficient, scalable and practical decision-making; however, most of the existing literature (1) focuses on improving algorithms for maximizing the expected cumulative reward, and (2) […]
Abstract The massive quantities of single-use plastics discarded each year requires new sustainable end-of-life solutions. Current technologies, such as melt-processing for recycling or incineration for partial energy recovery, are insufficient to deal with the crisis in its entirety. New methods involving chemical upcycling, by catalytic conversion of the used materials into higher value products, could […]
The diversity and vastness in the types of properties of living systems, including enhanced mechanical properties of skin and bone, or responsive optical properties derived from structural coloration, are a result of the multiscale, hierarchical structure of the materials. The field of materials chemistry has leveraged equilibrium concepts to create complex materials seen in nature, […]
Stable chronic mapping of brain activities at the action potential level with high temporal resolution is essential for both fundamental neuroscience research and biomedical applications, including cognitive studies, memory encoding and retrieval, and neural prostheses. Conventional neural probes can provide high spatiotemporal-resolution brain signal recordings independent of probing depth, although they generally trigger foreign body […]
Rapid, sensitive, and specific detection of causative pathogens is key to personalized medicine and the prompt implementation of appropriate mitigation measures to reduce disease transmission, mortality, morbidity, and cost. Conventional molecular detection methods require trained personnel, sophisticated equipment, and specialized laboratories, which limits their use to centralized laboratories. To enable molecular diagnostics at the point […]
Many robotic applications require a robot to operate in an environment with unknowns or uncertainty, at least initially, before it gathers enough information about the environment. In such a case, a robot must rely on sensing and perception to feel its way around. Moreover, it has to couple sensing/perception and motion synergistically in real time, […]
Because the physical world is complex, ambiguous, and unpredictable, autonomous agents must be engineered to exhibit a human-level degree of flexibility and generality — far beyond what we are capable of explicitly programming. Achieving such rich and intricate decision making requires rethinking the foundations of intelligence across all stages of the autonomous learning lifecycle. In […]
Abstract: Ultrafine aerosols can significantly influence Earth’s climate if they are able to grow to sizes large enough to interact with the incoming solar radiation and nucleate cloud droplets. In clear air, aerosol growth occurs via gas-to-particle conversion of condensable trace gases, including sulfuric acid, nitric acid, hydrochloric acid, ammonia, and myriad oxidation products of […]
Amorphous solids, those composed of haphazardly arranged constituents, are found everywhere from our windows as silicate glass, in the ground and foundations as mud and concrete, and our grocery stores as granular piles of oranges. Even though they can be found over a huge range of length scales, it remains a challenge to systematically design […]
Physical Sciences in Oncology Center PSOC@Penn Spring 2022 Hybrid-Seminar Series Towne 225 / Raisler Lounge @ Noon (EST) For Zoom link , please contact manu@seas.upenn.edu
Abstract: "As thrombosis proceeds, platelets in a clot can expose phosphatidylserine (PS), providing a negatively charged surface for thrombin generation. These PS+ platelets have been shown to sort to the perimeter of platelet masses via platelet contraction. However, it remains unclear how thrombin and fibrin affect PS+ platelet sorting within a clot. We used an […]
Abstract: "Hemostatic clots have a core/shell hierarchy comprised of a P-selectin positive core surrounded by a P-selectin negative shell. A new human blood microfluidic assay utilizing a 2-stage assay was developed to interrogate core/shell mechanics. By first perfusing whole blood over a collagen/TF surface and then swapping out the blood for buffer, we were able […]
The gravity-driven flow of grains from a hole in a hopper is an iconic granular phenomenon. It’s different from a fluid in that the rate is independent of fill height, and more spectacularly so in that it can suddenly and unexpectedly clog. How does the susceptibility to clogging decrease with increasing hole size, and is […]
In many cases, the size and weight of energy storage technologies required to power robotic systems are too large or massive for a robot to carry, leading to limited operational times and long recharging times over which the robot remains unused. Computer-free autonomous decision making based on environmental cues provides exciting alternatives to classic control […]
*This will be a HYBRID Event with in-person attendance in Levine 512 and Virtual attendance via Zoom We consider the problem of Vision-and-Language Navigation (VLN) in previously unseen realistic indoor environments. Arguably, the biggest challenge in VLN is grounding the natural language to the visual input. The majority of current methods for VLN are trained end-to-end […]
Abstract Life occurs in water, and water-mediated interactions are central to biomolecular assembly processes. Synthetic materials as common as soap and shampoo also rely on water-mediated interactions. This presentation will describe experiments that highlight our lack of understanding of interactions in water. The opportunity to formulate a refined set of design rules for self-assembly of […]
*This will be a HYBRID Event with in-person attendance in Towne 337 and Virtual attendance via Zoom Collectives in nature demonstrate behaviors that extend far beyond the capabilities of any single agent. Social slime mold, for example, has thousands of cells that aggregate and form mobile and immobile nutrient-searching structures as a function of chemical signals. […]
Polymer electrolytes are an important class of ion conducting materials critical to enabling various electrochemical systems. Fundamentally, ion-polymer coordination, inter-connectivity of solvation sites, and corresponding ion-solvating polymer dynamics are critical in understanding the limits of ionic conductivity. Here, the importance of these effects is highlighted in a series of combined experimental and computational studies on […]
Robots are increasingly being used to complete tasks in complex environments. To complete these tasks, two of the most fundamental choices that the robot must make are (1) task planning: which tasks to complete and in what order, and (2) path planning: what path to take when navigating between those tasks. In this seminar, I […]
Given only a single picture, people are capable of inferring a mental representation that encodes rich information about the underlying 3D scene. We acquire this skill not through massive labeled datasets of 3D scenes, but through self-supervised observation and interaction. Building machines that can infer similarly rich neural scene representations is critical if they are […]
The Department of Bioengineering at the University of Pennsylvania and Dr. Dennis Discher are pleased to announce the Doctoral Dissertation Defense of Jason Andrechak. Title: Leveraging Macrophage Immune Checkpoint Blockade to Link Innate and Adaptive Immunity Against Solid Tumors Date/time: Friday, 4/15 at 11am Location: Glandt Forum Singh Center for Nanotechnology 3205 Walnut St, Philadelphia, PA 19104 […]
We live with a health care system that has evolved into an increasingly fragmented, primarily treatment-oriented, and now heavily burdened environment. More importantly, issues related to privacy, space, and disease transmissibility have limited access to non-medical personnel who might offer creative, evidence-based, radical change to the health care system, as proposed years ago by the […]
Physical Sciences in Oncology Center PSOC@Penn Spring 2022 Hybrid-Seminar Series Towne 225 / Raisler Lounge @ Noon (EST) For Zoom link , please contact manu@seas.upenn.edu
Core electrification technologies require developments in battery packs, chargers, electric motors, and thermal management strategies to improve their performance, longevity, reliability and safety. The next battery technology leap relies on novel thermal management strategies and packaging architectures, realized as intelligent battery thermal management systems (BTMS), which can optimally control the thermo-electrochemical phenomena occurring inside the […]
The study of the functional organization of the human brain using resting-state functional MRI (rsfMRI) has been of significant interest in cognitive neuroscience for over two decades. The functional organization is characterized by patterns that are believed to be hierarchical in nature. From a clinical context, studying these patterns has become important for understanding various […]
Launched in May 2021, the Future Leaders in Mechanobiology is a monthly seminar series featuring up-and-coming leaders in mechanobiology–PhD students and postdocs from a wide range of fields, backgrounds, and institutions. By providing an international stage to share one’s work and opportunities to interact with researchers at all career stages, we aim to create an inclusive and […]
The Department of Bioengineering at the University of Pennsylvania and Dr. Louis Soslowsky are pleased to announce the Doctoral Dissertation Defense of Ryan Leiphart Title: Biglycan regulation of regional tendon development via the pericellular matrix Date: Wednesday, April 20th Time: 1PM Location: JMB Reunion Auditorium John Morgan Building 3620 Hamilton Walk Philadelphia, PA 19104 […]
Please use the link below to find more information and sign up for the tour! https://docs.google.com/forms/d/e/1FAIpQLSc-OxodC7fsVFL7AMX_gK4gblHO8zPw5IaZRE-15wUXTUnVRg/viewform
Multiphoton microscopy has changed how we visualize neurons by providing high-resolution, non-invasive imaging capability deep within intact brain tissue. Multiphoton imaging will likely play a major role in understanding how the brain works at the level of neural circuits. In this talk, in vivo structural and functional imaging of mouse brain using long wavelength excitation […]
Two problems pertaining to solid-solid phase transitions are presented here. First, we conduct Langevin dynamics calculations on a chain of masses and bistable springs in a viscous fluid, and extract a temperature dependent kinetic relation by observing that the dissipation at a phase boundary can be estimated by performing an energy balance. Using this kinetic […]
The Department of Bioengineering at the University of Pennsylvania and Dr. David Cormode are pleased to announce the Doctoral Dissertation Defense of Clara Dong. Title: Engineering injectable, radiopaque hydrogels for X-ray imaging and therapeutic delivery for cancer treatments Date: 4/21 1pm Location: Zoom https://upenn.zoom.us/j/91096994943?pwd=TVh5UFltSlBHTXJ6blp4VFlRbTNUdz09 The public is welcome to attend.
A haptic interface is a mechatronic system that modulates the physical interaction between a human and their tangible surroundings. Such systems typically take the form of grounded kinesthetic devices, ungrounded wearable devices, or surface devices, and they enable the user to act on and feel a remote or virtual environment. I will elucidate key approaches […]
2022 Bioengineering Grad Symposium April 22, 2022 Singh Center for Nanotechnology Register to Attend Deadline: April 15, 2022 We are excited to announce that the 2022 Bioengineering Graduate Symposium has been rescheduled and will be held in person on April 22, 2022, 12:45 pm - 6 pm at Singh Center. Food, drinks, and free swag will be available throughout the […]
Please use the below link to find more information and signup! https://docs.google.com/forms/d/1ntEeVQmO4mBXk7PGNi5GaXLRnrdaQ30fmhoflKIvMpQ/viewform?edit_requested=true
The Department of Bioengineering at the University of Pennsylvania and Dr. Robert Mauck are pleased to announce the Doctoral Dissertation Defense of Hannah Zlotnick. Title: Remote field guided assembly of complex orthopaedic tissues Date: Monday April 25th Time: 11 am Location: JMB Class of '62 Auditorium John Morgan Building 3620 Hamilton Walk Philadelphia, PA 19104 The […]
Physical Sciences in Oncology Center PSOC@Penn Spring 2022 Hybrid-Seminar Series Towne 225 / Raisler Lounge @ Noon (EST) For Zoom link , please contact manu@seas.upenn.edu
The Department of Bioengineering at the University of Pennsylvania and Dr. D. Kacy Cullen are pleased to announce the Doctoral Dissertation Defense of Wisberty Gordián Vélez. Title: Human tissue-engineered nigrostriatal pathway encased in hyaluronic acid for axon tract reconstruction in Parkinson’s disease Date: Monday, April 25th Time: 2:00 pm Location: JMB Reunion Auditorium John Morgan Building 3620 Hamilton […]
Numerical simulation of physical phenomena is a powerful tool embraced by scientists and engineers for decades. Using simulation tools to predict human movements is particularly critical for training AI-enabled robots interacting with humans, providing testbeds for wearable device design, and generating a wealth of labeled, high-fidelity human motion data. However, existing physics simulators and motor […]
Despite the recent progress in robot learning, robotics research and benchmarks today are typically confined to simple short-horizon tasks. However, tasks in our daily lives are much more complicated — consisting of multiple sub-tasks and requiring high dexterity skills — and the typical “learning from scratch” scheme is hardly scale to such complex long-horizon tasks. […]
With the shortage of rehabilitation clinicians in rural areas and elsewhere, remote rehabilitation (telerehab) fills an important gap in access to rehabilitation. We have developed a first of its kind social robot augmented telepresence (SRAT) system — Flo — which consists of a humanoid robot mounted onto a mobile telepresence base, with the goal of […]