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BE Seminar: “Repurposing bacterial two-component systems as sensors for synthetic biology applications “

Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Two-component systems (TCSs) are the largest family of signal transduction pathways in biology, and a treasure trove of biosensors for engineering applications. Though present in plants and other eukaryotes, TCSs are ubiquitous in bacteria. Bacteria use TCSs to sense everything from metal ions to carbohydrates and light, and activate responses such as biofilm formation, antibiotic-resistance, […]

MEAM Seminar: “Cell Polarization and Growth”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Polarization is an essential behavior of living cells, yet the dynamics of this symmetry-breaking process are not fully understood. We have developed a spatial stochastic model of cellular polarization during mating of Saccharomyces cerevisiae. Specifically we investigated the ability of yeast cells to sense a spatial gradient of mating pheromone and respond by forming a […]

CBE Faculty Candidate Seminar: Decomposition: Exploiting Structure in Chemical Systems to Solve Challenging Decision-Making Problems”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Computational optimal decision-making tools are essential for ensuring that systems are designed, operated, and controlled in an economic and sustainable manner. Using optimization to make decisions for chemical and energy systems is particularly challenging due to the inherent presence of nonlinear process physics, both integer and continuous decisions, uncertainties in important parameters, and multiple […]

CBE Faculty Candidate Seminar: Towards a “Greener” Route for Acetic Acid Production via the Carbonylation of Dimethyl Ether Over Small-Pore Molecular Sieves

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Catalyst design is a critical pillar, and current bottleneck, in the construction of a sustainable chemical industry. Practical catalytic materials are earth-abundant, active, selective, and stable. Developing materials that meet these criteria is challenging and involves a two-phase process that (1) extracts molecular-level understanding of the origin of reactivity for a given chemical pathway, […]

MEAM Seminar: “Robot Design Concepts for Intuitive Physical Human-Robot Interaction”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Physical human-robot interaction (pHRI) aims at taking advantage of the complementary capabilities of robots and humans. One of the key challenges in pHRI is to provide a high-bandwidth human-robot interaction that is safe and intuitive for the human user. To this end, it is proposed in this work to revisit the design of robots in […]

“Engineering at NSF: Big Ideas and More”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Three years ago, NSF announced Ten Big Ideas for Future Investments. From Harnessing the Data Revolution, to defining the Future of Work at the Human-Technology Frontier, and Understanding the Rules of Life, all of the Big Ideas require cross-disciplinary, convergent research to make significant progress on these important societal challenges. The talk will present an […]

CBE Faculty Candidate Seminar: “Understanding and Design of Materials of High Energy Density Batteries”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Environmental challenges and economic forces are reshaping the way we generate and consume energy on a global scale. To keep up with the accelerating adoption of electric vehicles, allow for grid scale energy storage, and meet the demands of future technological advances, new materials for high energy density batteries must be developed. High costs […]

PICS Seminar – Dr. Cesar de la Fuente of the University of Pennsylvania, Perelman School of Medicine

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Abstract: Until now, the natural world has supplied us with antibiotics. Bacteria, however, are increasingly resistant to these drugs. The next generation of antibiotics will likely come not from nature but from computer-based discovery. Working at the forefront of this development, I seek to harness computational power to find molecules with antibacterial activity. I use […]