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Britton Chance Distinguished Lecture: “Regenerative Immunology: The Role of Technology Translation in Guiding Discovery”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Biomaterial implants have a long history in the clinic, but regenerative biomaterials and regenerative medicine therapies, in general, have been slow to reach patients. Clinical translation provides a unique and critical opportunity to investigate the key therapeutic drivers of technology efficacy in people. Careful evaluation of clinical outcomes and reevaluation of design parameters is […]

PICS Seminar – Dr. Yoichiro Mori of the University of Pennsylvania & the University of Minnesota

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Abstract: Mathematical Justification of Slender Body Theory Systems in which thin filaments interact with the surrounding fluid abound in science and engineering. The computational and analytical difficulties associated with treating thin filaments as 3D objects has led to the development of slender body theory, in which filaments are approximated as 1D curves in a 3D […]

MEAM Seminar: “Microdevices Enabled by Rarefied Flows”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

In this talk we will review emerging applications of rarefied gas dynamics for microscale sensing, actuation and power generation. Performance of conventional fluidic devices such as pumps, combustors and heat engines decreases at the microscale due to greater viscous and heat transfer losses. Unconventional micro/nanodevices exploit the tight coupling between non-equilibrium gas, liquid and solid-state […]

CBE Faculty Candidate Seminar: “Understanding and Controlling the Complexity of Catalytic Active Sites”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Heterogeneous catalysis is of central importance to the global economy today, facilitating the conversion of raw materials into valuable fuels and chemicals, and the abatement of chemical pollutants in an efficient way. As environmental concerns associated with the use of fossil fuels and increased viability of alternative technologies motivate a transition away from traditional […]

BE Seminar: “Immunomodulatory Biomaterials for Limb Salvage”

Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Diabetes and peripheral arterial disease affect hundreds of millions of people worldwide. Patients with these conditions frequently develop chronic wounds on the lower limbs that lead to amputation, with a 5-year mortality rate as high as 77%. Macrophages, the primary cell of the innate immune system, are critical regulators of angiogenesis and wound healing. Their […]

CBE Faculty Candidate Seminar: “Facilitating Chemical Process Development Using Theoretical Modeling and Machine Learning”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Computational modeling is an important tool to aid chemical process development. Theoretical and data-driven models can be applied both for the optimization of specific processes, and for the initial screening of potential process chemistries. I will talk about my research in advancing both of these areas. First, I will introduce the development of an […]

MEAM Seminar: “Recent Evolution of Climate Science: From Greenhouse Gases and Temperature to Aerosol Particles and Precipitation”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

On the eve of the Intergovermental Panel on Climate Change (IPCC) Sixth Assessment Report, I will present a brief overview of how climate science has evolved since the publication of the Charney Report in 1979, and use a few examples from my recent work to show how one can use numerical models, observations and theories […]

CBE Seminar: “A Case for Carbon Dioxide Removal from Air”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: As a global society, we have been burning fossil fuels to meet our energy and transportation needs since the start of the industrial revolution. This has resulted in atmospheric CO2 concentrations much greater than at any other time during the last 650,000 years. That concentration reached a record 415 parts per million in May […]

BE Seminar: “Repurposing bacterial two-component systems as sensors for synthetic biology applications “

Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Two-component systems (TCSs) are the largest family of signal transduction pathways in biology, and a treasure trove of biosensors for engineering applications. Though present in plants and other eukaryotes, TCSs are ubiquitous in bacteria. Bacteria use TCSs to sense everything from metal ions to carbohydrates and light, and activate responses such as biofilm formation, antibiotic-resistance, […]

MEAM Seminar: “Cell Polarization and Growth”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Polarization is an essential behavior of living cells, yet the dynamics of this symmetry-breaking process are not fully understood. We have developed a spatial stochastic model of cellular polarization during mating of Saccharomyces cerevisiae. Specifically we investigated the ability of yeast cells to sense a spatial gradient of mating pheromone and respond by forming a […]