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The Department of Bioengineering at the University of Pennsylvania and Dr. Felix Wehrli are pleased to announce the Doctoral Dissertation Defense of Rajiv Deshpande. Title: “MRI-based Quantification of Renal Oxygen Utilization” Date: August 28, 2023 Time: 10:00 AM Location: Donner-Grice Auditorium, HUP (2nd Floor) The public is welcome to attend. |
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Fuelled in particular by current medical challenges in Traumatic Brain Injury, the field of brain mechanics has progressed tremendously in the last decade. Simulations that required months in development and runtime can now be created from patient specific medical images, meshed and run in a fraction of that time. However, and paradoxically, not only do […] |
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Designing advanced material systems poses challenges in integrating knowledge and representation from multiple disciplines and domains such as materials, manufacturing, structural mechanics, and design optimization. Data-driven machine learning and computational design methods provide a seamless integration of predictive materials modeling, manufacturing, and design optimization, enabling the accelerated design and deployment of advanced material systems. In […] |
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The Department of Bioengineering at the University of Pennsylvania and Dr. David Issadore are pleased to announce the Doctoral Dissertation Defense of Andrew Lin. Title: “Development of magnetic nanopore-based extracellular vesicle subpopulation sorting for the multimodal diagnosis and prognosis of neurological disease and cancer” Date: Wednesday, September 6th from Time: 2:30 PM Location: Raisler Lounge (Towne 2nd Floor) […]
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The chemical industry produces more than 70,000 products (1.2 billion tons in total) via thermal processes powered by fossil fuel combustion, accounting for ~5% of the US energy utilization and >30% of the US energy-derived industrial CO2 emissions. Amongst these processes, the production of organic chemical commodities accounts for most of the energy utilization (>1200 […] |
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EHRS Sr. Lab Safety Specialist Gwenn Allen will discuss how to work safely in the lab while navigating the changing landscape of materials science and engineering research. Her talk will cover common laboratory hazards, routes of exposure, PPE requirements, and biological safety. She will also present an overview of the University’s recent transition to Workday […]
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The repertoire of naturally occurring proteins is finite and many molecules induce multiple confounding effects, limiting their efficacy as therapeutics. Recently, there has been a growing interest in redesigning existing proteins or engineering entirely new proteins to address the deficiencies of molecules found in nature. Researchers have traditionally taken an unbiased approach to protein engineering, […] |
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GRASP Lab faculty confirmed presentations (where appropriate their presenters)... *This is a HYBRID Event with in-person attendance in Wu & Chen Auditorium and virtual attendance on Zoom. Dr. Mark Yim (Welcome and Introduction) Dr. Pratik Chaudhari Dr. Kostas Daniilidis Dr. Eric Eaton Dr. Nadia Figueroa Dr. Dinesh Jayaraman Dr. Michael Posa Dr. Jianbo Shi Dr. […] |
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Fibrosis and remodeling of extracellular matrix are involved in many diseases, such as tumors, wound healing, and chronic inflammation. During fibrosis, tissues undergo changes in their viscoelastic properties, i.e., how they resist deformation like a solid and dissipate stress over time like a fluid. Our research determines the impact of viscoelasticity on inflammation in fibrotic […]
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Quantum physics puts a limit on how small the noise added by an amplifier can be. Limiting this extra noise, which causes unavoidable signal degradation, is an essential requirement for the measurement of weak electromagnetic signals in various areas of science and engineering. In particular, a nearly-quantum-limited microwave amplifier is a key tool for performing […] |
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ABSTRACT: Throughout the COVID-19 pandemic, countries relied on a variety of ad-hoc border control protocols to allow for non-essential travel while safeguarding public health: from quarantining all travellers to restricting entry from select nations based on population-level epidemiological metrics such as cases, deaths or testing positivity rates. Here we report the design and performance of […]
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This is a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT Autonomous agents have made great strides in specialist domains like Atari games and Go. However, they typically learn tabula rasa in isolated environments with limited objectives, thus failing to generalize across a wide spectrum of tasks and capabilities. […]
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The global market size of paints and coatings (P&C) was US$164 Billion in 2022 and is forecast to grow to US$241Billion by 2030. A fast-growing sector in the P&C industries is acrylics. P&C should contain a solvent in order to be brushable/sprayable. However, in the case of solvent-borne P&C, their improved sustainability requires decreasing their […] |
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The Department of Bioengineering at the University of Pennsylvania along with Drs. Despina Kontos and Taki Shinohara proudly announce the Doctoral Dissertation Defense of Hannah Horng. Title: Batch effect detection and harmonization methods for quantitative features extracted from medical images Date: September 15, 2023 Time: 10:30am Location: John Morgan Building - Class of '62 Auditorium. Zoom […]
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GRASP Lab faculty confirmed presentations (where appropriate their presenters)… *This is a HYBRID Event with in-person attendance in Wu & Chen Auditorium and virtual attendance via Zoom. Dr. Ani Hsieh (Welcome and Introduction) Dr. Jean Gallier Dr. Michelle Johnson (presented by Francis Sowande) Dr. Vijay Kumar (presented by Jake Welde) Dr. Lingjie Liu Dr. Nik […]
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Finding time to support and mentor students can be challenging. Drs. Lee Bassett and Jennifer Lukes will start this informal conversation by sharing ideas for promoting positive relationships with students while maintaining boundaries to preserve our time. We will consider ways to use office hours efficiently, as well as ways to leverage technology to simplify […] |
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Insect respiration is characterized by the rapid transport of respiratory gases within the organism and efficient exchange with the external environment. This unique system is comprised of a network of tracheal tubes that directly supply oxygen to the cells throughout the body, eliminating the need for blood as an intermediate oxygen carrier. The remarkable diversity […] |
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Microorganisms, although challenging to observe, are ubiquitous in both natural ecosystems and industries. They inhabit diverse environments: natural ones ranging from small river tributaries and lakes to oceans, as well as in industrial settings, like wastewater treatment plants and food manufacturing. In these diverse contexts, microorganisms coexist with settling particles, a process heavily influenced by […]
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ABSTRACT: "A.I. has an explainability crisis"---Fortune Magazine. If you ask an ML researcher about explainability, you'll find that there are a large number of interpretability methods with no clear consensus on what to use. In fact, it isn't clear what many of these explanations even mean, let alone how they can be used. I will […]
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Development of a newly fertilized embryo is a dynamic, complex, and highly coordinated process that requires precise genetic regulation and control. As the embryo develops, DNA regulatory elements known as enhancers drive gene expression patterns in specific regions of an organism at a particular time. Mis-regulation of gene expression due to mutations in enhancers can […] |
4 events,
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Dr. Mogas-Soldevila will give an overview on her DumoLab research at the Weitzman School of Design at Penn. Her works focuses on regenerative material practices bridging science, engineering, and the arts. DumoLab builds scholarship for materials design critique, and translates biomedical materials used in implants, drug delivery, and tissue scaffolding, into robust materials for use […]
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This thesis addresses the challenges of model-based planning and control in legged locomotion, particularly the trade-off between computational speed and robot performance presented by different levels of model complexities. Full-order models, while rich in detail, are often too computationally demanding for real time planning, whereas conventional reduced-order models (ROMs) tend to oversimplify the dynamics, limiting […]
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The Department of Bioengineering at the University of Pennsylvania and Dr. Ophir Shalem are pleased to announce the Doctoral Dissertation Defense of Henry Sanchez. Title: Pooled tagging of endogenous proteins for exploration of the human proteome driven by prime editing Date: September 21, 2023 Time: 3:00pm Location: Colket Translational Research Building (Room 4040) The public is welcome to attend. |
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There is an enormous interest in developing customized, domain-specific systems-on-a-chip. Continued improvement in computing efficiency requires functional specialization of hardware designs. But designing complex chips is difficult. This talk presents the Chipyard framework, an integrated SoC design, simulation, and implementation environment for specialized compute systems. Chipyard includes configurable, composable, open-source, generator-based IP blocks that can […] |
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High-level control of atomic and surface structures is a hallmark of the application of nanomaterials in a range of electrochemical and electrocatalytic devices, such as water electrolyzer. They play critical roles in our effort to develop energy conversion and storage technologies that have net zero carbon impacts. Nanostructured metal oxides made for catalyzing the oxygen […]
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Control of shape and movement is essential for cell physiology, from cell migration to control of tissue shape. The mechanical behaviors of living cells are controlled by materials constructed by protein-based assemblies within the cell interior. These soft materials both regulate how forces generated by individual mechanoenzymes are transmitted to cell and tissue scales as […] |
4 events,
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An on-orbit demonstration of asteroid deflection is a key test of our ability to defend the planet from an incoming asteroid. The recent DART (Double Asteroid Redirection Test) mission was NASA's demonstration of kinetic impactor technology, impacting an asteroid to adjust its speed and path. The DART spacecraft impacted the asteroid Dimorphos on September 26, […]
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Nudges are interventions promoting healthy behavior without forbidding options or significant incentives. As an example of a nudge, the Apple Watch encourages users to stand by delivering a notification if they have been sitting for the first 50 minutes of an hour. Based on 76 billion minutes of observational standing data from 160,000 subjects in […]
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For many important tasks such as manipulation and locomotion, robots need to make and break contact with their environment. Although such multi-contact systems are common, they pose a significant challenge when it comes to analysis and control. This thesis exploits the local hybrid structure of such problems and presents scalable and fast algorithmic solutions. First, […] |
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ABSTRACT: We present three approaches to combine formal methods, control theory, and machine learning for safe and performant autonomous systems. Safe control for learning-enabled systems: We present our recent progress on how to learn safe adaptive behavior for highly interactive multi-agent systems. We will introduce how to quantify the uncertainty of closed-loop control systems using […]
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This is a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. This week's speaker will be virtual. ABSTRACT Robots are traditionally designed with immutable physical hardware and control policies that make them specialized for repetitive, structured tasks and environments. This talk presents work toward robots that actively change shape to […] |
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Abstract The production of polymer products relies largely on age-old molding techniques. A major reason for this is that additive methods have not delivered meaningful alternatives to traditional processes—until now. In this talk, I will describe Continuous Liquid Interface Production (CLIP) technology, which embodies a convergence of advances in software, hardware, and materials to bring […] |
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Loading of biological and synthetic hydrogels involves large deformations, and there exists a large literature devoted to their experimental characterization. Analytical investigations have recognized the importance of contributions originating from the liquid phase, and experiments have verified them. The liquid flux fields in these materials usually exhibit fully three-dimensional profiles and are time-dependent. This coupled […]
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This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance on Zoom. ABSTRACT Now that a significant fraction of human knowledge has been shared through the Internet, scraped and squashed into the weights of Large Language Models (LLMs), do we still need embodiment and interaction with the physical world to build […] |
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