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BE Seminar: “Self-Assembling Nanotechnologies for Precision Biomaterials” (Santiago Correa, Stanford)

Self-assembled materials with defined nanoscale architectures can engage with biological systems in fundamentally new ways, providing unprecedented biomedical opportunities. In particular, the ability to more precisely control both the location and timing of drug release makes these biomaterials especially useful for delivering potent or sensitive cargo, which has major implications for cancer therapy and immuno-engineering. […]

MEAM Seminar: “Assembly Engineering of Patchy Particles into Complex Structures, and Beyond”

Zoom - Email MEAM for Link peterlit@seas.upenn.edu

The ability to predict, design and make the perfect material with just the right properties to do what we want, how we want, and when we want is the holy grail of materials research. Such “materials on demand” require control over thermodynamics, kinetics, nonequilibrium behavior, and structure across many length and time scales. With continuing […]

CEMB Future Leaders: “The place of plant chromatin in sensing mechanical stress”

https://upenn.zoom.us/j/96715197752

Launched in May 2021, the Future Leaders in Mechanobiology is a monthly seminar series featuring up-and-coming leaders in mechanobiology–PhD students and postdocs from a wide range of fields, backgrounds, and institutions. By providing an international stage to share one’s work and opportunities to interact with researchers at all career stages, we aim to create an inclusive and […]

CBE Seminar: “Tackling Disease-Associated Biomolecules: From RNA Therapeutics to Single-Molecule Detection”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract The functionality versatility of polymeric and nucleic acid materials provides diverse engineering opportunities for the detection and therapeutic targeting of disease-associated biomolecules. My work has encompassed nanoscale and microscale technologies to address challenges in cancer therapeutics and diagnostics, from targeting the expression of dysregulated genes to probing rare protein biomarkers. I will first describe […]

ESE Ph.D. Thesis Defense: “Statistical Learning for System Identification, Prediction, and Control”

Zoom - Meeting ID 949 5950 4530

Despite the recent widespread success of machine learning, we still do not fully understand its fundamental limitations. Going forward, it is crucial to better understand learning complexity, especially in critical decision making applications, where a wrong decision can lead to catastrophic consequences. In this thesis, we focus on the statistical complexity of learning unknown linear […]

MSE Seminar: “How do tissues fracture and repair across length scales?”

https://upenn.zoom.us/j/96715197752

In structural materials engineering, we often aim to create materials that are simultaneously strong, tough and lightweight- a combination classically considered mutually exclusive. Biogenic composite materials such as bone exhibit a combination of these properties exceeding that of their constituents, a feat generally credited to their hierarchal structure, down to the nanoscale. In this talk, […]

BE Seminar: “Engineering New Tools to Understand Airway Mucosal Barrier Function” (Gregg Duncan)

Moore 216 200 S. 33rd Street, Philadelphia, PA, United States

This seminar will be held in person and on zoom (the link will be sent out via email). Mucus is a biological gel within the lung designed to behave like an “escalator” with the ability to capture potentially harmful inhaled materials (e.g. pathogens, particulates) and carry these materials via mucociliary clearance up to the throat […]

BE Seminar: “Visualizing the Unseen: Enabling Precision Oncology Through Microenvironment-Triggered Diagnostics and Therapeutics” (Liangliang Hao)

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

The successful integration of precision diagnostics with new personalized therapies opens numerous doors to improve the management of a variety of diseases. In cancer, tissue-environmental features of tumor progression and invasion, including aberrant extracellular matrix remodeling, stromal composition changes, and immune cell engagement, create engineering opportunities for use in developing novel biomarkers and therapeutic targets. […]

MEAM Seminar: “‘Tiny-but-tough’ GaN- and Graphene-based Nanoelectronics for Extreme Harsh Environments”

Zoom - Email MEAM for Link peterlit@seas.upenn.edu

Gallium nitride (GaN) nanoelectronics have operated at temperatures as high as 1000°C making it a viable platform for robust space-grade (“tiny-but-tough”) electronics and nano-satellites. Even with these major technological breakthroughs, we have just begun the “GaN revolution.” New communities are adopting this nanoelectronic platform for a multitude of emerging device applications including the following: sensing, […]

MEAM PhD Thesis Defense: “Accelerated Design of Architected Materials with Geometric Heterogeneity for Enhanced Failure Characteristics”

Zoom - Email MEAM for Link peterlit@seas.upenn.edu

Nature provides countless examples of the use of material heterogeneity to enhance the failure properties of materials. Many biological materials, such as bone, marine shells, and fish scales, are extremely resilient to fracture and failure. These often consist of regions that are highly mineralized and stiff and regions of biopolymers that are extremely soft. In […]