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CBE Seminar: “Tackling Disease-Associated Biomolecules: From RNA Therapeutics to Single-Molecule Detection”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract The functionality versatility of polymeric and nucleic acid materials provides diverse engineering opportunities for the detection and therapeutic targeting of disease-associated biomolecules. My work has encompassed nanoscale and microscale technologies to address challenges in cancer therapeutics and diagnostics, from targeting the expression of dysregulated genes to probing rare protein biomarkers. I will first describe […]

ESE Ph.D. Thesis Defense: “Statistical Learning for System Identification, Prediction, and Control”

Zoom - Meeting ID 949 5950 4530

Despite the recent widespread success of machine learning, we still do not fully understand its fundamental limitations. Going forward, it is crucial to better understand learning complexity, especially in critical decision making applications, where a wrong decision can lead to catastrophic consequences. In this thesis, we focus on the statistical complexity of learning unknown linear […]

BE Seminar: “Engineering New Tools to Understand Airway Mucosal Barrier Function” (Gregg Duncan)

Moore 216 200 S. 33rd Street, Philadelphia, PA, United States

This seminar will be held in person and on zoom (the link will be sent out via email). Mucus is a biological gel within the lung designed to behave like an “escalator” with the ability to capture potentially harmful inhaled materials (e.g. pathogens, particulates) and carry these materials via mucociliary clearance up to the throat […]

BE Seminar: “Visualizing the Unseen: Enabling Precision Oncology Through Microenvironment-Triggered Diagnostics and Therapeutics” (Liangliang Hao)

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

The successful integration of precision diagnostics with new personalized therapies opens numerous doors to improve the management of a variety of diseases. In cancer, tissue-environmental features of tumor progression and invasion, including aberrant extracellular matrix remodeling, stromal composition changes, and immune cell engagement, create engineering opportunities for use in developing novel biomarkers and therapeutic targets. […]

MEAM Seminar: “‘Tiny-but-tough’ GaN- and Graphene-based Nanoelectronics for Extreme Harsh Environments”

Zoom - Email MEAM for Link peterlit@seas.upenn.edu

Gallium nitride (GaN) nanoelectronics have operated at temperatures as high as 1000°C making it a viable platform for robust space-grade (“tiny-but-tough”) electronics and nano-satellites. Even with these major technological breakthroughs, we have just begun the “GaN revolution.” New communities are adopting this nanoelectronic platform for a multitude of emerging device applications including the following: sensing, […]

CBE Seminar: “Revealing the Unknown Dynamics of High-Energy Density Lithium-Metal Batteries”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract High-energy density batteries will play a remarkable role in hurdling global climate change. My research focuses on the fundamental understandings of their electrochemical reaction mechanisms and the design of materials, protocols, and characterization tools to enable their safe operations over long-term use. First, I will discuss about the previously overlooked dynamics of detached lithium […]

ESE Spring Colloquium – “The One Learning Algorithm Hypothesis– Towards Universal Machine Learning Models and Architectures”

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

We revisit the “One Learning Algorithm Hypothesis” of Andrew Ng (Google Brain) according to which the brain of higher-level animals and of humans processes and perceives sensory data (vision, sound, haptics) with the same abstract algorithmic architecture. We develop models, based on our earlier work on automatic target recognition with radar and other sensors, face […]

BE Seminar: “Orchestrating Cellular Regeneration at Organ Scale” (Yvon Woappi)

Large scale tissue damage, such as organ failure and burn injury, is a leading cause of morbidity and death. However, the mechanisms underlying full regeneration of organs remain poorly understood. As the largest organ system in the body, the integumentary system is a composite tissue assembly evolutionarily adapted for healing. Consequently, its complex physiology requires […]

GRASP on Robotics: Andreas Malikopoulos, University of Delaware, “Separation of Learning and Control for Cyber-Physical Systems”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

*This will be a VIRTUAL Event with attendance via Zoom Webinar here.  Cyber-physical systems (CPS), in most instances, represent systems of subsystems with an informationally decentralized structure. To derive optimal control strategies for such systems, we typically assume an ideal model, e.g., controlled transition kernel. Such model-based control approaches cannot effectively facilitate optimal solutions with […]