Cells use genetically-encoded molecular circuits to execute diverse biological functions. We are developing novel tools of synthetic biology that allow us to construct regulatory circuitry inside living cells that recapitulate complex functions like those seen in nature. In this talk, I will describe how we use this approach to achieve three objectives. First, I will […]
Lymphatic, nervous, and tumoral tissues, among others, exhibit physiology that emerges from three-dimensional interactions between genetically unique cells. Technologies capable of volumetrically imaging transcriptomes, genotypes, and morphologies in a single de novo measurement can provide a critical lens into the biological complexity of living systems. We present experimental and computational work to develop DNA microscopy: […]
Update 10/14/24: Please note the new time and location for Nina Ghosn's Doctoral Dissertation Defense below. The Department of Bioengineering at the University of Pennsylvania and Dr. Brian Litt are pleased to announce the Doctoral Dissertation Defense of Nina Ghosn. Title: DATA DRIVEN APPROACHES FOR OPTIMIZING ANTISEIZURE MEDICATION MANAGEMENT IN EPILEPSY Advisor: Brian Litt Date: October […]
The Department of Bioengineering at the University of Pennsylvania and Dr. Peter Noel are pleased to announce the Doctoral Dissertation Defense of Leening Liu. Title: Spectral CT thermometry for real-time, non-invasive temperature monitoring of thermal ablation Date: November 4, 2024 Time: 2:00 PM Location: Reunion Auditorium, John Morgan Building Zoom info: Topic: Leening Liu's Dissertation Defense Time: November 4, […]
This seminar will be held in Moore 216 and remotely via zoom (check email for zoom link). Light refreshments will be served.
The Department of Bioengineering Fall 2024 Student Demos. Location: The Stephenson Foundation Bio-Makerspace (aka the BE Labs) in Skirkanich Hall 225. BE 3090, aka BE MAD: Human-Cockroach Machine Interface. December 4th from 1:30-2:30 PM, and December 5th from 3:15-4:15. BE 4950 Senior Design: Minimum Viable Product. December 9th, 3:30-5:00 PM.
The Department of Bioengineering at the University of Pennsylvania and Dr. Jenny Jiang are pleased to announce the Doctoral Dissertation Defense of Yuwan Guo. Title: High-throughput and high-dimensional single-cell analysis of antigen-specific CD4+ T cells Advisor: Dr. Jenny Jiang Date :Thursday, Dec 5, 2024 Time: 11am - 1pm Location: Glandt Forum, 3rd floor Singh Center The […]
The Department of Bioengineering at the University of Pennsylvania and Dr. Jennifer Cremins are pleased to announce the Doctoral Dissertation Defense of Katelyn Titus. Title: Understanding the genome's structure-function relationship in early neural lineage commitment Date: December 5, 2024 Time: 3:30 PM Location: CRB Austrian Auditorium The public is welcome to attend.
The Department of Bioengineering at the University of Pennsylvania and Dr. Sydney Shaffer are pleased to announce the Doctoral Dissertation Defense of Dylan Schaff. Title:"Clonal differences underlie differential responses to initial, sequential, and prolonged drug treatment" Date:December 6, 2024 Time: 1pm-3pm Location: Wu and Chen auditorium, Levine Hall The public is welcome to attend.
Humans and other animals do not always choose the most rewarding course of action, even when we have ample time and computational resources. Why do we make mistakes? The noiseLab uses a combination of theoretical, behavioral, and neurobiological techniques to address this question. In this talk, Dr. Becket Ebitz will discuss converging evidence that mistakes are the product of representational and temporal nonlinearities in neural activity that constrain our ability to make good decisions. The talk will argue that some of these nonlinearities have long-term adaptive benefits, even when they fail to produce the best decision in the moment.
