This event will be held virtually on zoom. Check email for zoom link or email ksas@seas.upenn.edu. CAR T cells—T cells engineered to express a chimeric antigen receptor that redirects their function to a specific antigen—have proven to be an effective therapy for certain B cell cancers, but many issues remain in order to apply CAR […]
Pixar's films rely heavily on physically simulated effects such as the motion of hairs, cloth, and water, to cite a few. Whereas physical accuracy is of paramount importance in engineering applications, the most important aspects of feature film productions are directability and speed. In this talk, I'll survey our recent work in this area, including […]
Many complex nonequilibrium systems, including turbulent flows, are characterized by chaotic dynamics, a large number of degrees of freedom, and hierarchical, multiscale structure in space and time. In two vignettes, we describe some recent work aimed at developing and applying machine learning and data science tools for systems displaying these characteristics. The first vignette builds […]
Abstract: Fluids and solids tend to be addressed using distinct computational perspectives. Solid deformation is most commonly simulated with Lagrangian finite-element methods, whereas fluid flow is amenable to Eulerian-frame approaches such as finite difference and finite volume methods. Problems that mix fluid and solid behaviors simultaneously present interesting numerical challenges. Here we focus on […]
Talk title TBC Physical Sciences in Oncology Center PSOC@Penn Fall 2020 Webinar Series Mondays @ Noon (EST) For webinar links, please contact manu@seas.upenn.edu
In this talk I will provide an overview of our recent work in data-driven methods---mainly machine learning---to enhance computational materials physics models. This body of work has proceeded along two main fronts. The first is system inference, where we seek to identify physical mechanisms via their mathematical signatures as differential or algebraic operators. Our approach […]
With the commercialization of wide-bandgap power semiconductors, multi-MHz switching frequencies are more compelling and critical to meet new applications demanding leaps in power density and efficiency. In the past, studies of these converters reported significant gaps between measured and modeled performance, often attributed to dynamic RDS,ON in GaN HEMTs. In particular, the power semiconductors – […]
A long-standing grand challenge in computing is to enable machines to act autonomously and intelligently: to rapidly and repeatedly take appropriate actions based on information in the world around them. Driven by trends in the data economy, rapid progress in AI, and an increasingly programmable physical world we are at an inflection point that demands […]
Abstract Until now, the natural world has supplied us with antibiotics. Bacteria, however, are increasingly resistant to these drugs. The next generation of antibiotics will likely come not from nature but from computer-based discovery. Computer-driven approaches have the potential to outperform humans, as demonstrated for pattern recognition of images and text. In order for machines […]
The Department of Bioengineering at the University of Pennsylvania and Dr. David Meaney are pleased to announce the Doctoral Dissertation Defense of Samantha Schumm. The public is welcome to attend the Zoom meeting via the details below. Title: Computational Investigations of Neuronal Network Responses to Traumatic Brain Injury Date: Thursday, October 29th, 2020 Time: 9:00am EST Join Zoom […]
