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CBE Seminar: “Embryogenesis: A Cascade of Dynamical Systems”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: We aim to establish and experimentally test mathematical models of embryogenesis. While the foundation of this research is based on models of isolated developmental events, the ultimate challenge is to formulate and understand dynamical systems encompassing multiple stages of development and multiple levels of regulation. These range from specific chemical reactions in single cells […]

“Compressive Sensing: From Algorithms to Circuits”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Compressive Sensing is an acquisition technique which relies on the sparsity of the underlying signals, to enable sampling below the classical Nyquist rate. To do so, the signals must be acquired in an incoherent way with respect to the sparsity basis, which is classically obtained in practice by acquiring the signal through projection on a […]

MSE Lab Safety Seminar

Auditorium, LRSM Building 3231 Walnut Street, Philadelphia, PA, United States

MEAM Seminar: “Dynamical Systems Approach to Geophysical and Aerospace Flows”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

A dynamical systems approach is taken to explain the dynamics of two classes of ‘gap-leaping’ geophysical flow as well as the hypersonic second-mode instability. First, in the context of a loop current system, it is shown that multiple steady flow patterns with hysteresis exist and appear to satisfy a cusp catastrophe geometry of solutions. Which […]

CBE Seminar: “Complexity in the Chemistry and Physics of Lipid Membranes as a Handle to Activate the Delivery of Cargo to Cells”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Lipid materials having nanostructures that deviate from the conventional flat bilayer arrangement such as hexagonally packed lipid tubes and bi-continuous cubic phases are ubiquitous in nature. Their role remains elusive but over the years several pathologies and organelle functions have been coupled to lipid membrane structural complexity. In this talk, we will discuss lipid membrane polymorphism and […]

PRiML Seminar: “Building Algorithms by Playing Games”

Room 401B, 3401 Walnut 3401 Walnut Street, Philadelphia, PA, United States

A very popular trick for solving certain types of optimization problems is this: write your objective as the solution of a two-player zero-sum game, endow both players with an appropriate learning algorithm, watch how the opponents compete, and extract an (approximate) solution from the actions/decisions taken by the players throughout the process. This approach is very […]

MEAM Seminar: “Engineering Microdevices Using Atomic Layer Deposition and Electrowetting”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

This talk will cover 1) devices created one atomic layer at a time and 2) electrowetting optical elements. Atomic layer deposition (ALD) and Atomic Layer Etching (ALE) are self-limiting processes that enable accurate atomic-scale thickness control either through deposition or etching of various materials. We are developing novel manufacturing processes that study how ALD materials […]

ESE & Statistics Seminar: “Large Neural Networks: Insights from Linearized Models”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Abstract: Modern machine learning models, and in particular multilayer neural networks, exhibit a broad range of puzzling phenomena. Their training requires to minimize a highly non-convex high-dimensional cost function, and yet it is efficiently addressed using simple gradient descent (GD) or stochastic gradient descent (SGD) algorithms. This model contains more parameters than the number of […]

CBE Seminar: “Evolution of the Conformational-free Energy Landscapes of Proteins”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: One of the holy grails of drug-design is to obtain high-selectivity binding of a drug to the target protein, an extremely challenging endeavor for proteins that share high sequence and structural similarity. We investigate several systems of high biological importance to elucidate how selectivity emerged during evolution and how it can inform the design […]