PICS Seminar: “Topology, Geometry, and Fracture in Networked Materials: A Tale of Scales”

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

The skeleton of many natural and artificial structures may be abstracted as networks of nonlinearly interacting elements. Examples include rubber, gels, soft tissues, and lattice materials. Understanding the multiscale nature of deformation and failure of networked structures hold key for uncovering origins of fragility in many complex systems including biological tissues and enables designing novel […]

BE Seminar: Next Generation Orthobiologics: Advanced Growth Factor and Biomaterials Engineering

Class of 62 Auditorium, John Morgan Building 3620 Hamilton Walk, Philadelphia, PA

The standard of care for augmenting surgical bone repair or regeneration remains bone graft harvested from the patient despite a lack of sufficient quantity or quality of graft in many clinical cases.  Bone morphogenetic protein (BMP) therapeutics have been successfully developed and commercially marketed as substitutes for bone graft.  Although the clinical success of BMP, […]

CBE Seminar: “Embryogenesis: A Cascade of Dynamical Systems”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: We aim to establish and experimentally test mathematical models of embryogenesis. While the foundation of this research is based on models of isolated developmental events, the ultimate challenge is to formulate and understand dynamical systems encompassing multiple stages of development and multiple levels of regulation. These range from specific chemical reactions in single cells […]

CBE Seminar: “Complexity in the Chemistry and Physics of Lipid Membranes as a Handle to Activate the Delivery of Cargo to Cells”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Lipid materials having nanostructures that deviate from the conventional flat bilayer arrangement such as hexagonally packed lipid tubes and bi-continuous cubic phases are ubiquitous in nature. Their role remains elusive but over the years several pathologies and organelle functions have been coupled to lipid membrane structural complexity. In this talk, we will discuss lipid membrane polymorphism and […]