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Seminar
PSOC Spring 2019 Seminar Series: Theresa Whitehead, Ph.D.
Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United StatesCBE Seminar: “Predicting and Controlling Stability and Protein-Protein Interactions for Therapeutic Antibodies”
Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United StatesBE Seminar: “Microfluidics and Immuno-Materials for Organs-on-a-Chip”
Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United StatesThis presentation will describe microfluidic technologies to conveniently produce life-like pulsatile flows along with applications to study of lung injury, enhancement of in vitro fertilization, and analysis of frequency-dependent cellular responses. The microfluidic technologies range from adaptation of piezo-electric actuator arrays from Braille displays to design of microfluidic circuits that can be designed to switch […]
PSOC Spring 2019 Seminar Series: Alexander Anderson, Ph.D.
Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United StatesMEAM Seminar: “Force, Shape, and Motion in Collective Cell Migration”
Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United StatesCells migrate collectively to form tissues, to heal wounds, and, in cancer, to metastasize. During these biological processes, the collective migration exhibits a transition from a solid-like state, wherein cell positions remain fixed, to a fluid-like state, wherein cells flow freely and rearrange their positions with their neighbors. Recent mechanics-based models and experiments have demonstrated […]
CBE Seminar: “Particle Transport in Soft, Disordered Media”
Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United StatesBE Seminar Series: Applied Topology in Biological Systems
Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United StatesThough rooted in pure mathematics, algebraic topology has recently enabled novel analysis techniques for biological data. Specifically, the method called persistent homology which employs ideas from topology to characterize the voids in a complex network. In this talk, I will briefly introduce persistent homology and give an overview of how we have recently applied this […]
BE Seminar Series: Synchronization is Robust in a Computational Model of Neuronal Network Dynamics and Injury
Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United StatesAt the macroscale, synchronization between brain regions is believed to be important for memory and attention. Injury, including mild traumatic brain injury, can both increase and decrease synchronization as measured by functional MRI, but these changes are not well understood and are unknown at a smaller spatial scale. Here, we examined how injury affects the […]
BE Seminar Series: Heterogeneous, Multi-Scale and Patient-Speci C Pharmacodynamic Systems Models for Cancer with Clinical Applications
Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United StatesAbstract: Systems models of key signaling pathways in cancer have been extensively used to understand and explore the mechanisms of action of drugs and growth factors on cancer cell signaling. In general, such models predict the effect of mechanical or chemical stimuli (for e.g. drug dosage) in terms of activity of one or more key […]