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PICS Colloquium: “Building and using virtual models of the tricuspid valve toward better understanding, diagnosis, and treatment of its diseases”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Computer simulations have become critical elements of the medical device design and regulatory approval process. Naturally, the predictability and therefore value of such simulations depends highly on their accuracy. Especially for the design of heart valve replacements and repair technologies computer simulations have become a critical tool. While much progress has been made in modeling […]

MEAM Seminar: “Data-Aware Computational Models for Science and Engineering”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

In the past half-century, partial differential equation (PDE)-based computational models have emerged as indispensable for science and engineering. However, remarkable gaps still exist between state-of-the-art simulations and reality, meaning that many simulations are ineffective in supporting decision-making or design under uncertainty for complex systems (e.g., Mars landing). To bridge the gap and fulfill challenging real-world […]

CIS Seminar: “Rethinking System Design for Expressive Cryptography”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Expressive cryptography, including Secure Multi-Party Computation (SMPC) and Fully Homomorphic Encryption (FHE), has the potential to enable transformative new applications, drawing significant interest from industry. Unfortunately, it is often slow and resource-intensive, making those applications difficult to realize. For example, SMPC enables multiple organizations (e.g., hospitals) to run joint computations on their data (e.g., for […]

ASSET Seminar: Decision-Aware Learning for Global Health Supply Chains, Osbert Bastani (University of Pennsylvania)

Levine 307 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Machine learning algorithms are increasingly used in conjunction with optimization to guide decision making. A key challenge is aligning the machine learning loss with the decision-making loss. Existing solutions have limited flexibility and/or scale poorly to large datasets. We propose a principled decision-aware learning algorithm that uses a Taylor expansion of the optimal decision […]

CIS Seminar: “Methods of Data Lookup with Hashing”

Levine 307 3330 Walnut Street, Philadelphia, PA, United States

We will discuss methods of data lookup, with a focus on hash sets / tables, including motivation, properties, and variants. This will be in the context of a "CS 2" or data structures course. We will assume a basic familiarity with programming and comfort with implementing resizable lists; as well as knowledge of (but not […]

CBE Seminar Series: “A New Phase of Biological Controls: A Design Framework for Programmable Synthetic Biomolecular Condensates and the Mechanisms of a Functional Liquid-Liquid Interface” (Yifan Dai, Duke University)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: A fundamental question in nature is how the cellular processes are organized with sequential and spatial precision in a dynamic and densely packed environment. Evidence is now mounting that biomolecular condensation, a demixing process mediated by phase separation coupled with percolation, dictates the organization principles of cellular biochemistry. From the perspective of synthetic biology, […]

ESE PhD Thesis Defense: “Accelerating FPGA Developments from C to Bitstreams by Partial Reconfiguration”

Cora Ingrum Conference Room (Towne 215 - enter at Towne 211)

Divide-and-Conquer and incremental compilation strategies are widely used in software compilations. To enable these strategies for FPGAs, this dissertation presents an open-source framework called PRflow, which can speed up the compilation times by at most an order of magnitude. PRflow supports different optimization levels to make better trade-offs among compile-time, area, and performance. -O0 (PRflow_RISCV) […]

BE Seminar: “Programming multicellular interactions and organization using synthetic cell adhesion molecules” (Adam Stevens, UCSF)

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

Cell adhesion molecules (CAMs) are ubiquitous in multicellular organisms and specify precise cellular interactions in processes as diverse as tissue development and immune cell trafficking. We have generated an array of synthetic CAMs by combining orthogonal extracellular interactions with native intracellular domains. Diverse homotypic or heterotypic extracellular binding domains specify the connectivity between cells, while […]

CIS Seminar: “Birds of a Feather Flock Together: How Homophily Leads to Segregation, Inequality, and Inefficiency and What We Can Do About It”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Humans exhibit a strong tendency to associate with those similar to them. This tendency, termed homophily in the social sciences, impacts both the structure of society and its outcomes. In this talk, Nicole Immorlica discusses the mathematics of homophily. She first quantifies its theoretical implications for geographic segregation. We will see that even tolerant societies […]