CBE PhD Dissertation Defense | “The role of clot structure and mechanics on hemodynamics and pharmacology”
Greenberg Lounge (Room 114), Skirkanich Hall 210 South 33rd Street, Philadelphia, PA, United StatesAbstract: "Hemostatic clots have a core/shell hierarchy comprised of a P-selectin positive core surrounded by a P-selectin negative shell. A new human blood microfluidic assay utilizing a 2-stage assay was developed to interrogate core/shell mechanics. By first perfusing whole blood over a collagen/TF surface and then swapping out the blood for buffer, we were able […]