MEAM Doctoral Dissertation Defense: “Applications of a Double-stranded Elastic Rod Model to DNA”
4E9, DRLB 209 S. 33rd Street, Philadelphia, PA, United StatesIn the first part of the presentation, we discuss a double-stranded elastic rod (birod) model and apply it to study allosteric interactions between two ligands on DNA. Next, we combine the birod model with statistical mechanics and use it to study the temperature-induced strand separation in dsDNA. Allosteric interaction between two ligands on DNA is […]