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CBE Seminar Series: “A New Phase of Biological Controls: A Design Framework for Programmable Synthetic Biomolecular Condensates and the Mechanisms of a Functional Liquid-Liquid Interface” (Yifan Dai, Duke University)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: A fundamental question in nature is how the cellular processes are organized with sequential and spatial precision in a dynamic and densely packed environment. Evidence is now mounting that biomolecular condensation, a demixing process mediated by phase separation coupled with percolation, dictates the organization principles of cellular biochemistry. From the perspective of synthetic biology, […]

BE Seminar: “Programming multicellular interactions and organization using synthetic cell adhesion molecules” (Adam Stevens, UCSF)

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

Cell adhesion molecules (CAMs) are ubiquitous in multicellular organisms and specify precise cellular interactions in processes as diverse as tissue development and immune cell trafficking. We have generated an array of synthetic CAMs by combining orthogonal extracellular interactions with native intracellular domains. Diverse homotypic or heterotypic extracellular binding domains specify the connectivity between cells, while […]

Spring 2023 GRASP on Robotics: Jeremy D. Brown, Johns Hopkins University, “Understanding the Utility of Haptic Feedback in Telerobotic Devices”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance via Zoom. This week's presenter will be in-person as well.    ABSTRACT The human body is capable of dexterous manipulation in many different environments. Some environments, however, are challenging to access because of distance, scale, and limitations of the body […]

CBE Seminar Series: “Engineered CRISPR Systems for Disease Treatment and Diagnostics” (Xue Sherry Gao, Rice University)

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

Abstract: The recent discovery of the CRISPR genome editing systems has been revolutionizing both basic biological research and the treatment of human genetic disorders. However, there are remaining challenges in improving the precision and multiplexity of the current CRISPR systems for genome manipulation. In this seminar, I will overview our recent development of highly specific […]

MEAM Seminar: “Leveraging Unsteady Flows for Enhanced Performance in Wind-Energy Systems”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Wind energy is poised to play a considerable role in the global transition to clean-energy technologies within the next few decades. Modern wind turbines, like aircraft and other aerodynamic structures, are typically designed with the assumption that the flows they encounter will be uniform and steady. However, atmospheric flows are highly unsteady, and systems operating […]

Future Leaders in Mechanobiology: Windie Hofs (Crick Institute/UCL)

https://upenn.zoom.us/j/96715197752

Launched in May 2021, the Future Leaders in Mechanobiology is a monthly seminar series featuring up-and-coming leaders in mechanobiology–PhD students and postdocs from a wide range of fields, backgrounds, and institutions. By providing an international stage to share one’s work and opportunities to interact with researchers at all career stages, we aim to create an inclusive and […]

Spring 2023 GRASP SFI: Jinwei Ye, George Mason University, “Seeing 3D with Polarized Light”

Levine 307 3330 Walnut Street, Philadelphia, PA, United States

This is a hybrid event with in-person attendance in Levine 307 and virtual attendance via Zoom. This week's presenter will be in-person as well. ABSTRACT Polarization is a fundamental property of light that describes the direction in which the electric field of light oscillates. Polarization, as an intrinsic property of light, provides an extra dimension […]

CBE Seminar Series: “Developing Strategies for Polymer Redesign and Recycling Using Reaction Pathway Analysis” (Linda Broadbelt, Northwestern University)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: The current lack of sustainability of and the limited portfolio of recycling processes for synthetic polymers have posed serious threats to the environment. Using reaction pathway analysis, we are pursuing a portfolio of strategies for redesign and recycling of polymers for sustainability. Pyrolysis is a promising method for resource recovery from plastic waste that […]

MEAM Seminar: “Mechanics for Energy Sustainability: From Fatigue of 2D Materials to Dendrites in Solid-state Batteries”

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

Achieving energy sustainability requires efforts from not only sourcing clean energy, but also storing and dispatching energy whenever and wherever needed, as well as being energy-efficient whenever possible. Two-dimensional (2D) materials hold great promises as mechanical reinforcement in high strength-to-weight ratio structural materials and as next-generation energy-efficient electronic materials, both of which contribute to less […]

MSE Seminar: “Design of Stable Nanocrystalline Alloys: Thermodynamics, Computation, and Data Science” (Massachusetts Institute of Technology)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Over the last three decades, nanocrystalline alloys (polycrystals with grain sizes of less than 100 nm) have been shown to exhibit superior material properties, such as enhanced specific strength, hardness, wear resistance, radiation resistance, and magnetic properties. However, such structures are inherently thermodynamically unstable; a nanocrystalline configuration comes with a large volume fraction of high-energy […]