Spring 2023 GRASP Seminar: Henry Fuchs, UNC Chapel Hill, “Augmented Reality Glasses: a 50-year Adventure”

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

This is an in-person only event with attendance in Raisler Lounge (Towne 225). The presenter will be in-person as well. ABSTRACT Many of us foresee of a future in which AR eyeglasses are worn all day, replacing of our current prescription eyewear. That future may not arrive for a while and predicting its benefits and […]

ASSET Seminar: Using Large Language Models to Build Explainable Classifiers, Chris Callison-Burch (University of Pennsylvania)

Levine 307 3330 Walnut Street, Philadelphia, PA, United States

ABSTRACT: I'll present research on using large language models (LLMs) to build explainable classifiers.   I will show off work from my PhD students and collaborators on several recent research directions: Image classification with explainable features  (https://arxiv.org/abs/2211.11158) Text classification with explainable features (work in progress) The importance of faithfulness in explanations (https://arxiv.org/abs/2209.11326) (Time permitting) A […]

Spring 2023 GRASP SFI: Melkior Ornik, University of Illinois Urbana-Champaign, “System Resilience and Guaranteed Performance in the Face of Unexpected Adversity”

Levine 307 3330 Walnut Street, Philadelphia, PA, United States

This is a hybrid event with in-person attendance in Levine 307 and virtual attendance via Zoom. This week's presenter will be in-person as well. ABSTRACT The ability of a system to correctly respond to a sudden adverse event is critical for high-level autonomy in complex, changing, or remote environments. By assuming continuing structural knowledge about […]

BE Seminar: “Probing Metabolism Across Scales” (Yihui Shen, Princeton University)

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Metabolism supports the biosynthetic and energetic demand of all living creatures. Over decades, we have accumulated knowledge of how individual enzymes work in vitro, but we don’t have a good sense about how they work together in vivo. Thus, fundamental to our understanding of metabolic operation is the ability to measure metabolic activity in vivo. […]

Spring 2023 GRASP on Robotics: Rodney Brooks, Robust.AI, “Academic research: exploration vs exploitation”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance via Zoom. This week's presenter will be in-person as well.    ABSTRACT Intelligent action is critical in robotics, more so than much of AI where results are often mediated by humans in the loop. That said, robotics also needs to […]

MEAM Seminar: “Data-Aware Computational Models for Science and Engineering”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

In the past half-century, partial differential equation (PDE)-based computational models have emerged as indispensable for science and engineering. However, remarkable gaps still exist between state-of-the-art simulations and reality, meaning that many simulations are ineffective in supporting decision-making or design under uncertainty for complex systems (e.g., Mars landing). To bridge the gap and fulfill challenging real-world […]

ASSET Seminar: Decision-Aware Learning for Global Health Supply Chains, Osbert Bastani (University of Pennsylvania)

Levine 307 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Machine learning algorithms are increasingly used in conjunction with optimization to guide decision making. A key challenge is aligning the machine learning loss with the decision-making loss. Existing solutions have limited flexibility and/or scale poorly to large datasets. We propose a principled decision-aware learning algorithm that uses a Taylor expansion of the optimal decision […]

CBE Seminar Series: “A New Phase of Biological Controls: A Design Framework for Programmable Synthetic Biomolecular Condensates and the Mechanisms of a Functional Liquid-Liquid Interface” (Yifan Dai, Duke University)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: A fundamental question in nature is how the cellular processes are organized with sequential and spatial precision in a dynamic and densely packed environment. Evidence is now mounting that biomolecular condensation, a demixing process mediated by phase separation coupled with percolation, dictates the organization principles of cellular biochemistry. From the perspective of synthetic biology, […]

BE Seminar: “Programming multicellular interactions and organization using synthetic cell adhesion molecules” (Adam Stevens, UCSF)

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

Cell adhesion molecules (CAMs) are ubiquitous in multicellular organisms and specify precise cellular interactions in processes as diverse as tissue development and immune cell trafficking. We have generated an array of synthetic CAMs by combining orthogonal extracellular interactions with native intracellular domains. Diverse homotypic or heterotypic extracellular binding domains specify the connectivity between cells, while […]