CBE Seminar: “Deep Learning-Enabled Design of Functional DNA-Binding Properties” (Cameron Glasscock, University of Washington)
CBE Seminar: “Deep Learning-Enabled Design of Functional DNA-Binding Properties” (Cameron Glasscock, University of Washington)
Abstract DNA-binding proteins (DBPs) play critical roles in biology and biotechnology, and there has been considerable interest in the engineering of DBPs with new functions or altered specificities. While there has been success in reprogramming and the specificity of naturally occurring DBPs using selection methods, the computational design of new DBPs that engage with DNA […]