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PICS Colloquium: “Transforming Healthcare from the Outside: the OBSERVER project”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

We live with a health care system that has evolved into an increasingly fragmented, primarily treatment-oriented, and now heavily burdened environment.  More importantly, issues related to privacy, space, and disease transmissibility have limited access to non-medical personnel who might offer creative, evidence-based, radical change to the health care system, as proposed years ago by the […]

MEAM Seminar: “Disease Indicator Prediction in Vascular Flows via Physics-Informed Deep Learning”

Towne 313 220 S. 33rd Street, Philadelphia, PA, United States

Unlike diseases with strong genetic predisposition, such as cancer, there exist no accurate personalized diagnostic tools for disorders such as Hypertensive Pregnancy Disorders (HPD) and its mechanism remain understudied. For the purpose of performing diagnostics, we require disease indicators (biomarkers) that are strongly correlated with the underlying condition, i.e. absolute vascular pressure for hypertension. Measuring […]

MEAM Seminar: “Open Access Benchmark Datasets and Metamodels for Problems in Mechanics”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Metamodels, or models of models, map defined model inputs to defined model outputs. When metamodels are constructed to be computationally cheap, they are an invaluable tool for applications ranging from topology optimization, to uncertainty quantification, to real-time prediction, to multi-scale simulation. In particular, for heterogeneous materials, metamodels are useful for exploring the influence of the […]

PICS Colloquium: “Computation of Flow-Induced Sound at Low Mach Numbers”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Abstract: Flow-induced noise is a significant problem for air, road and marine vehicles as well as many other engineering applications.  At low Mach numbers, large disparities in energy levels and length scales between the flow and the concomitant sound present unique challenges for acoustic predictions.  This talk will start with a brief overview of computational […]

PICS Colloquium: “Group-Theoretic Approach for Nonlinear Problems in Mechanics with High Symmetry Avoids Use of Imperfections”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Many interesting problems in nonlinear mechanics, from classical to more recent, pertain to applications with high initial symmetry: from the buckling of thin walled structures to the morphing in architected materials – the list is long! A common feature of these problems, in addition to their importance for engineering applications, is their great theoretical interest […]

PICS Seminar: “A Non-local Plasticity Model for Porous Metals with Deformation-induced Anisotropy: Mathematical and Computational Issues”

Zoom - Email MEAM for Link peterlit@seas.upenn.edu

A non-local (gradient) plasticity model for porous metals that accounts for deformation-induced anisotropy is presented. The model is based on the work of Ponte Castañeda and co-workers on porous materials containing randomly distributed ellipsoidal voids. It takes into account the evolution of porosity and the evolution/development of anisotropy due to changes in the shape and […]

PICS Colloquium: “From Molecular Vibrations to Solvation, Protein Dynamics and Models of the Cytoplasm”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Abstract: Vibrational spectroscopies at mid-infrared frequencies provide excellent probes to characterize functional groups and their immediate chemical environment. However, from a thermodynamic and dynamic point of view, only the ground state of these vibrations is significantly populated. Most of the “jiggling and wiggling” of atoms and molecules (referred to in the famous quote by Feynman) […]

PICS/MEAM Seminar: “A Low Rank Tensor Approach for Nonlinear Vlasov Simulations”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

In this work, we present a low-rank tensor approach for approximating solutions to the nonlinear Vlasov equation. Our method takes advantage of the tensor-friendly nature of the differential operators in the Vlasov equation to dynamically and adaptively construct a low-rank solution basis through the discretization of the equation and an SVD-type truncation procedure. We utilize […]

PICS Seminar: “Computational fluid dynamics for slurry rheology in flow battery and underlying drag-reduction mechanisms in turbulent flow control”

https://upenn.zoom.us/j/96715197752

Email jnespos@seas.upenn.edu for the Zoom link. This talk will start by introducing diverse fluid-mechanics research conducted in the Park research group, including complex fluids, electrokinetics, biofluids, transition-to-turbulence, and turbulent flow. I will then focus on two projects at very different flow regimes. For both projects, the modeling, analysis, and computation will be presented along with […]

PICS Colloquium: “Building and using virtual models of the tricuspid valve toward better understanding, diagnosis, and treatment of its diseases”

PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

Computer simulations have become critical elements of the medical device design and regulatory approval process. Naturally, the predictability and therefore value of such simulations depends highly on their accuracy. Especially for the design of heart valve replacements and repair technologies computer simulations have become a critical tool. While much progress has been made in modeling […]