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BE Seminar: “Endothelial cells and the promise of regeneration on demand” (Brisa Palikuqi, UCSF)

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

In this seminar, I explore the pivotal role of tissue stem cells and their microenvironment, known as the niche, in regeneration. With a focus on the endothelial cell niche, my work introduces an innovative in vitro vascularized perfusable model tailored for human tissue explants and organoids. My findings also highlight the crucial contribution of paracrine […]

BE Seminar: “Systems Immunology Approaches for Tissue Repair and Regeneration” (Andres Munoz-Rojas, Harvard)

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

The immune system uses a complex network of interacting cells that work together to regulate tissue physiology, homeostasis, and repair. In muscle, a tightly coordinated network of immunocytes and mesenchymal stromal cells (MSCs) is required for adequate skeletal muscle repair after acute injury or disease. Regulatory T cells (Tregs) are important players in regulating excessive […]

BE Doctoral Dissertation Defense: “Engineering hydrogel microstructure to promote meniscus repair” (Karen Xu)

JMB Reunion Auditorium 3620 Hamilton Walk, Philadelphia, PA, United States

The Department of Bioengineering at the University of Pennsylvania along with Drs. Jason Burdick and Rob Mauck proudly announce the Doctoral Dissertation Defense of Karen Xu. Title: Engineering hydrogel microstructure to promote meniscus repair Date: March 11, 2024 Time: 12:00pm Location: Reunion Auditorium in John Morgan Building If you would like a zoom link, please email:  karen.xu@pennmedicine.upenn.edu The […]

BE Doctoral Dissertation Defense: “Ionizable lipid nanoparticles for in utero gene editing of congenital disease” (Rohan Palanki)

Smilow Center Auditorium 3400 Civic Center Blvd, Philadelphia, PA, United States

The Department of Bioengineering at the University of Pennsylvania and Drs. Michael J. Mitchell and William H. Peranteau are pleased to announce the Doctoral Dissertation Defense of Rohan Palanki. Title: Ionizable lipid nanoparticles for in utero gene editing of congenital disease Date: March 20th, 2024 Time: (1PM-3 PM) Location: Law Auditorium, Smilow Center for Translational Research (5th Floor) The public is welcome […]

BE Doctoral Dissertation Defense: “Tissue Engineered Cortical-Hippocampal Neural Networks for Pharmacological Investigations” (Victor Acero)

Class of 62 Auditorium, John Morgan Building 3620 Hamilton Walk, Philadelphia, PA

The Department of Bioengineering at the University of Pennsylvania and Dr. D. Kacy Cullen are pleased to announce the Doctoral Dissertation Defense of Victor Acero. Title: Tissue Engineered Cortical-Hippocampal Neural Networks for Pharmacological Investigations Date: March 20, 2024 Time: 2:00 PM Location: John Morgan Building Class of 62 Auditorium Zoom option: https://upenn.zoom.us/j/5112542338 The public is welcome to attend.

BE Seminar: “Synthetic and Chemical Biology Routes to Unveiling Host-Pathogen Dialogue” (Aerin Yang, Stanford)

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Disease processes within the human body are shaped by the dynamic interplay between invading pathogens and the host's defense mechanisms. The intricate molecular interaction involves continuous modifications of both host and pathogen proteins, driven by posttranslational modifications (PTMs) and coevolutionary mutations, to finely regulate their interactions with binding partners. In this talk, I will elucidate […]

BE Doctoral Dissertation Defense: “Decoding the tumor microenvironment to engineer the next generation of CAR T cells” (Puneeth Guruprasad)

Rubenstein Audtorium, Smilow Center for Translational Research

The Department of Bioengineering at the University of Pennsylvania and Dr. Marco Ruella are pleased to announce the Doctoral Dissertation Defense of Puneeth Guruprasad.   Title: Decoding the tumor microenvironment to engineer the next generation of CAR T cells Date: Friday, March 22nd Time: 10:00-11:00 AM Location: Smilow Translational Research Center, Arthur H. Rubenstein Auditorium […]

BE Doctoral Dissertation Defense: “The Origin and Factors Affecting Differentiation of Progenitor Cells in Tendon-to-Bone Integration” (Tim Kamalitdinov)

Smilow Center for Translational Research in SCTR 11-146AB

The Department of Bioengineering at the University of Pennsylvania and Dr. Nat Dyment are pleased to announce the Doctoral Dissertation Defense of Tim Kamalitdinov. Title: The Origin and Factors Affecting Differentiation of Progenitor Cells in Tendon-to-Bone Integration Date: April 16, 2024 Time: 9:00 AM Location: SCTR (Smilow Center for Translational Research) 12-146AB The public is welcome […]

BE Seminar: “Using Computers to Derive Protein Structure from Sparse Data – A Case Study for Mass Spectrometry” (Steffen Lindert, Ohio State)

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Mass spectrometry-based methods such as covalent labeling, surface induced dissociation (SID) or ion mobility (IM) are increasingly used to obtain information about protein structure. However, in contrast to other high-resolution structure determination methods, this information is not sufficient to deduce all atom coordinates and can only inform on certain elements of structure, such as solvent […]