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: Generative priors are effective countermeasures to combat the curse of dimensionality, and enable efficient learning and inversion that otherwise are ill-posed, in data science. This talk begins with the classical low-rank prior, and introduces scaled gradient descent (ScaledGD), a simple iterative approach to directly recover the low-rank factors for a wide range of matrix […] |
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Mass spectrometry-based methods such as covalent labeling, surface induced dissociation (SID) or ion mobility (IM) are increasingly used to obtain information about protein structure. However, in contrast to other high-resolution structure determination methods, this information is not sufficient to deduce all atom coordinates and can only inform on certain elements of structure, such as solvent […] |
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