ESE Fall Seminar – “Magnetic technologies for battery-free bioelectronics and neuromodulation”

Room 337, Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Miniature implanted and injected technologies capable of manipulating and recording biological signals promise to improve the way we study biology and the way we diagnose and treat disease; however, to create an effective bioelectronic network we must overcome myriad engineering challenges. In this talk, I will describe how we can leverage unique material properties to […]

ESE Spring Seminar – “Developing next-generation wireless, bioelectronic cellular medicine”

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Recent advances in engineering science have led to new classes of medical devices with emergent mechanical, electrical, and thermal properties that offer new opportunities for interfacing with living cells. I will discuss conceptual advances in microfabrication, device physics, power transfer and microscale transport phenomena that enable novel biosensors and cell delivery systems, with an emphasis […]

ESE Spring Seminar – “Neural Mechatronics and Mixed Reality for Patient Care”

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

The rich set of mechanoreceptors found in human skin offers a versatile engineering interface for transmitting information and eliciting perceptions, potentially serving a broad range of applications in patient care and other important industries. Targeted multisensory engagement of these afferent units, however, faces persistent challenges, especially for wearable, programmable systems that need to operate adaptively […]

ESE Spring Seminar – “Scaling Deep Learning Up and Down”

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Deep learning with neural networks has emerged as a key approach for discovering patterns and modeling relationships in complex data. AI systems powered by deep learning are used widely in applications across a broad spectrum of scales. There are strong needs for scaling deep learning both upward and downward. Scaling up highlights the pursuit of […]

ESE Spring Seminar – “Miniaturized Biomedical Devices for Navigation, Sensing and Stimulation”

Towne 327

Medical electronic devices are an integral part of the healthcare system today and are used in a variety of applications around us. The design of such devices has several stringent requirements, the key being miniaturization, low-power operation, and wireless functionality. In this talk, I will present CMOS-based miniaturized, low-power and wireless biomedical devices in three […]

BE Seminar: “Designing Programmable Protein Therapeutics with Generative Language Models” (Pranam Chatterjee, Duke University)

216 Moore Building

CRISPR has revolutionized biotechnology by enabling the simple design of guide RNAs to target and edit almost any DNA sequence. By developing new generative protein design algorithms, my hybrid lab focuses on extending this CRISPR-like programmability to proteins and other key molecules. In this talk, we will first delve into our algorithms that design binders […]

MEAM Seminar: “Exploring Structure, Mechanics, and Function in Soft Biological Systems Across Scales”

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Soft biological systems exhibit intricate hierarchical organization, with structures spanning multiple length scales, from tissues to cells and molecules. This structural complexity gives rise to rich mechanical behaviors that profoundly influence biological function. My research integrates soft matter physics and biology to establish a unified framework that connects structure, mechanics, and function in soft biological […]

ESE Spring Seminar – “Wavelength-Encoded Nanolaser Particles for Highly Multiplexed Single-Cell Analysis”

Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

Understanding single-cell heterogeneity in biological systems is considered the holy grail of biomedicine. However, conventional single-cell analysis methods are constrained by the destructive readout process of DNA barcodes and the broad emission linewidths of fluorescence barcodes, limiting their ability to capture dynamic information and achieve high multiplexing capabilities. This seminar explores the transformative potential of […]

MEAM Seminar: “Biomedical Innovations for Global Health Research and Technology (BIGHEART): NOAS, EXODUS, iTEARS, and BOAS”

Wu & Chen Auditorium

This presentation will discuss the concept of BIGHEART and present various illustrative examples of this approach. The initial focus will be on NOAS (Nanoscale Optical Antennas) within the context of quantitative life sciences and transformative medicine. NOAS facilitates the visualization of quantum biological electron transfer processes occurring in mitochondria within living cells, supports the precise […]

CPE4H Seminar: “Engineering Native Biological Complexity from the Inside–out and Outside–in” (Cole A. DeForest, University of Washington)

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

Abstract: Engineering heterogenous multicellular tissue with native complexity remains one of the holy grails of regenerative medicine and basic biological research. As success in this regard would yield powerful bioengineered constructs useful in functional transplantation, high-throughput drug screening, and fundamental biology investigation, research efforts in our lab have centered around developing and implementing tools to […]