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CBE Seminar: “Creating a New Circular Carbon Economy via Carbon Capture, Utilization and Storage” (Alissa Park, UCLA)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: To meet the ever-increasing global energy demands while addressing climate change, the development of carbon capture, utilization and storage (CCUS) technologies is one of the critical needs. In particular, there have been significant efforts to develop innovative CO 2 capture materials and CO 2 conversion technologies to create a new circular carbon economy based […]

MSE Seminar: “Single Metal Site Catalysts for Sustainable and Clean Hydrogen Energy”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Fossil fuels have been overwhelmingly used in many industry sectors in past decades, causing significant CO2 and other pollutant emissions, low efficiency, and nonsustainability. Clean and efficient energy storage and conversion via electrochemical reactions associated with hydrogen, oxygen, and water have attracted substantial attention for energy and environmental sustainability. Among compelling energy technologies, hydrogen proton […]

CBE Doctoral Dissertation Defense: “Engineering Biomolecular Condensates: Insights Into Catalytic Activities and Structural Design” (Muyang Guan)

https://upenn.zoom.us/j/96301746733

Abstract: Eukaryotic cells orchestrate cellular processes through spatiotemporal organization achieved by compartmentalization. Biomolecular condensates, formed via liquid-liquid phase separation (LLPS), serve as vital hubs for enzymatic reactions and mediate cellular functions. To investigate catalytic activities within biomolecular condensates, a light-emitting enzyme (NanoLuc) was incorporated into LAF-1 RGG model condensates. Incorporation into condensates led to a […]

MEAM Seminar: “Modeling the Unique Behaviors of Liquid Crystal Elastomers”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Liquid crystal elastomers (LCEs) exhibit complex thermomechanical behaviors that can be harnessed for a wide variety of applications in soft robotics, biomedical devices, and impact protection. The material comprises stiff mesogens bound in an elastomeric network of flexible polymer chains. The mesogens can order and disorder in response to temperature and mechanical deformation. This allows […]

CBE Seminar: “Unlocking New Therapeutic Strategies by Reconstructing Cell Signaling Networks from the Ground Up” (Mohamad Abedi, University of Washington, Seattle)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Immunotherapies have achieved remarkable success in treating hematological cancers, yet the solid tumor microenvironment remains a significant barrier to therapeutic breakthroughs. Machine learning (ML)-driven computational protein design offers a powerful approach to creating novel protein components tailored for specific functions. By combining ML-driven design with synthetic biology and immuno-engineering, we have developed innovative tools […]

CBE Seminar: “Engineering Technologies for Enhanced Modeling, Detection, and Treatment of Neurological Disease” (Alice Stanton, MIT)

Wu & Chen Auditorium

Abstract: Neurological conditions are the leading cause of illness worldwide, though over 92% of clinically tested CNS drug candidates fail to become treatments. Contributing to this high failure rate is a lack of understanding of human disease mechanisms, technologies to address them, and the restrictive blood-brain barrier (BBB), which most compounds fail to cross. New […]

CBE Doctoral Dissertation Defense: “A molecular understanding of the structure-property relationships of model end-linked polymer networks” (Han Zhang)

Room 35, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

Abstract: Polymer networks, including thermoplastics, thermosets, elastomers and gels, are among the most versatile and widely utilized polymeric materials, with applications spanning drug delivery systems, membranes and implantable devices. A comprehensive understanding of the intricate relationship between the macroscopic properties and the structure and topology of polymer networks is crucial for advancing their utilization and […]

CBE Seminar: “Toward Efficient and Synthesizable In-silico Molecular Design” (Wenhao Gao, MIT)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: The discovery of functional molecules plays a fundamental role in advancing chemical science and engineering, yet it remains a costly and time-intensive process. Recent advances in computational methods, particularly in generative artificial intelligence, have introduced a new approach—generative molecular design—which holds the promise of efficiently identifying molecules with desired properties. However, despite significant progress, […]

CBE Seminar: “Genetically Encodable Designer Biomaterials” (Shunzhi Wang, University of Washington)

Wu & Chen Auditorium

Abstract: Nature harnesses genetic sequences to encode structural information and emergent physical and chemical transformations required by life processes. Such orchestration is achieved through hierarchical self-assemblies driven by weak molecular interactions and optimized via evolution. However, emulating this level of programmability to create designer biomolecular materials remains a grand challenge. In this seminar, I will […]

CBE & VIEST Joint Seminar: “Lignin Conversion to Performance-advantaged Fuels, Chemicals, and Polymers” (Gregg Beckham, NREL)

Vagelos Institute for Energy Science and Technology, Room 121 231 S 34th Street, Philadelphia, PA, United States

Abstract: Terrestrial plants harbor renewable carbon resources in their cell walls that can directly contribute to decarbonization of the transportation and materials sectors, but the heterogeneous, aromatic lignin polymer found in plants has long obstructed both natural- and humankind-driven endeavors to deconstruct plant biomass to valuable products. However, viable methods to valorize lignin are essential […]