CBE Seminar: “Revolutionizing Bioimaging to Elevate Human Health”

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Holistic imaging of diverse functional, anatomical, and molecular architecture that span multiple levels, from cells to an entire system, remains a major challenge in biology. In this talk, I will introduce a series of technologies that enable integrated multiscale imaging and molecular phenotyping of both animal tissues and human clinical samples. I will discuss how […]

CBE Doctoral Dissertation: “Understanding and Controlling Polymer-Porous Solid Interactions for Catalytic Recycling of Polymers” (Tian Ren)

Berger Auditorium (Room 13), Skirkanich Hall 210 South 33rd Street, Philadelphia, PA, United States

Abstract: Understanding and controlling polymer-solid interactions is critical for optimizing the catalytic processes involved in polymer upcycling. In this Ph.D. thesis, I explored the intricacies of polymer behavior in nanoporous materials by monitoring the capillary infiltration dynamics of polystyrene (PS) and polyethylene (PE) into random packings of silica nanoparticles. To test the effect of surface […]

CBE Seminar: “Fabrication and Long-term Reliability of High Efficiency Monocrystalline Silicon Solar Cells” (Agarwal, Colorado School of Mines)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Global energy demand will continue to increase, and the ability of fossil fuels to meet these demands is limited due to the associated climate change concerns. In response to these concerns, new energy installations are increasingly based on renewable energy resources such as wind and solar. To further develop solar energy as a renewable energy […]

CBE Doctoral Dissertation: “From Nanoplates to Bottlebrushes: Engineering Thermodynamics in Polymer Nanocomposites” (Christian Tabedzki)

DRL A2

Abstract: Polymer nanocomposites (PNCs) represent a diverse class of materials where manipulating design parameters is crucial for tailoring material properties. Of utmost importance for nanocomposites is nanoparticle dispersion, which is affected by the nanoparticle itself as well as the overall polymer melt, providing two design routes. This dissertation explores PNCs through two distinctive systems: (1) […]

CBE Seminar: “Bioinspired Protein-Based Cancer Immunotherapy” (Yanpu He, MIT)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: Immunotherapy has revolutionized the field of cancer treatment over the past two decades, though only a small fraction of patients treated will achieve complete remission. As such, new paradigms to overcome resistance to immunotherapies are urgently needed. My research seeks to tailor immunotherapies towards individual differences in immune systems and the inherent heterogeneity of […]

ESE Grace Hopper Lecture – “Disrupting NextG”

Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

As 5G takes to the airwaves, we now turn our imagination to the next generation of wireless technology. The promise of this technology has created an international race to innovate, with significant investment by government as well as industry. And much innovation is needed as 6G aspires to not only support significantly higher data rates […]

CBE Seminar: “Optimal Control as a catalyst for Smart and Sustainable Systems” (Benjamin Decardi-Nelson, Cornell)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract: In modern engineering, sustainability is a crucial aspect, especially in chemical and biological process systems. This concept has evolved to encompass a holistic approach, emphasizing not only the use of sustainable resources but also the development of systems that are environmentally friendly, smart, and efficient. Such systems aim to minimize waste and optimize resource […]

CBE Seminar: “Molecular Microscopy with Single Cell Transcriptomic Data Resolves RNA Liquid Biopsies” (Sevahn Vorperian, Stanford)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract Invasive biopsy is the gold standard for diagnosing several diseases; however, these procedures offer a limited, localized view of the disease pathology to the physician and are not risk-free to the patient. Cell-free RNA (cfRNA) in blood plasma reflects dynamic gene expression changes and can facilitate early disease diagnosis, yet current cfRNA assays fall […]

CBE Seminar: “Systems Engineering for Addressing Critical Challenges in Viral Vector Manufacturing” (Francesco Destro, MIT)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract The demand for viral vectors is poised to soon exceed current production capacities, driven by the surging number of clinical trials for gene and cell therapies. Unfortunately, current manufacturing processes for viral vectors have high costs and low titers. This talk will demonstrate how process systems engineering tools can be leveraged for addressing the […]

CBE Seminar: “Minimally Invasive Neuroelectronics” (Anqi Zhang, Stanford)

Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

Abstract Neuroelectronic interfaces have enabled significant advances in both fundamental neuroscience research and the treatment of neurological disorders. However, current neuroelectronic devices have a clear trade-off between invasiveness and spatial resolution, and are unable to achieve seamless integration into the nervous system with cell-type specificity. In this talk, I will first introduce an ultra-small and […]