Fetal movements and physical activities generate mechanical signals that regulate musculoskeletal development. It is widely accepted that a bone’s adaptive response occurs within an optimal strain range that stimulates bone formation, exceeding typical daily activity levels. This principle has led to models predicting how bones respond to mechanical loads, as insufficient mechanical signals can result […]
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Our lab combines adhesion and tribology with modern polymers and surface coatings to understand soft interfaces in biology towards improving human health and accessibility. On the scale of cells, mechanical stiffness of cells and tissue can indicate diseases like fibrosis or osteoarthritis. On the scale of the human body, mechanical forces generated by friction form […] |
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Crosslinked biocompatible polymer networks offer unique potential for biomedical applications that demand high resilience under repetitive load-bearing conditions. However, conventional hydrogels often exhibit poor mechanical strength and irreversible damage under cyclic deformation. To address these challenges, this work presents a class of engineered polymer network designed for enhanced mechanical robustness: cryogel-based double-network (DN) hydrogels. In […] |
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