Seminar

Abstract: Recent technical advances are leading to a rapid transformation of the chemical palette available in cells, thus making it conceivable to produce nearly any organic molecule of interest—from biofuels to biopolymers to pharmaceuticals. However, these feats require the ability to “hijack” native cellular machinery and metabolism and navigate the complexity inherent in cellular regulation. […]

Abstract: Electrifying the chemical industry has been much touted as a path to a low-carbon future, but nearly all pathways of interest are electrochemical reductions. If we want water-to-hydrogen, CO2-to-chemicals, or nitrogen-to-ammonia, from where will we get the electrons? Water-to-oxygen is thermodynamically expensive, kinetically slow, and generates a zero-value product. This talk will discuss two […]

Abstract: I will present the phase separation behavior of different sequences of a coarse-grained model for sequence defined macromolecules. They exhibit a surprisingly rich phase behavior, and not only conventional liquid-liquid phase separation is observed, but also reentrant phase behavior. Most sequences form open phases consisting of large, interconnected aggregates (e.g. string-like or membrane-like clusters), […]

Abstract: We discuss how geometry, optimization, and machine learning are key technologies that are revolutionizing the way we think about data and the way we transform data into actionable models and decisions. Specifically, we explain how complex data (e.g., text, molecules, time series, images/video, supply chain flows) can be represented as geometrical objects and how […]

Abstract: Electrostatic assembly can be used to engineer coatings that yield release of different drugs, DNA or protein, resulting in highly tunable multi -agent delivery nanolayered release systems for tissue engineering, biomedical devices, and wound healing applications. Most recently, we have developed a modular nanoparticle approach using liposomal core particles and layering them with an […]