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CRISPR is a gene editing technique that allows researchers to quickly and precisely edit genome sequences. Beyond gene editing, CRISPR-Cas systems can be repurposed as a programmable platform for other various applications. In this talk, I will introduce how we use CRISPR technology to program microfluidic devices for DNA detection, DNA computing and digital display. […] |
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Abstract: Precise control of structural parameters through nanoscale engineering to improve optical and electronic properties of functional nanomaterials continuously remains an outstanding challenge. Previous work on nanoparticle synthesis and assembly has been conducted largely through solution chemistry at ambient pressure and relies on specific chemical or physical interactions such as van der Waals interactions, dipole-dipole […] |
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EHRS staff will discuss how to work safely in the lab while navigating the changing landscape of materials science and engineering research. The talk will also cover; - Standard orientation topics (physical/bio/chem safety, waste disposal, Workday training, etc.) - The new methylene chloride regulations and how they will affect EHRS and Penn operations. - Safe use of […]
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CRISPR has revolutionized biotechnology by enabling the simple design of guide RNAs to target and edit almost any DNA sequence. By developing new generative protein design algorithms, my hybrid lab focuses on extending this CRISPR-like programmability to proteins and other key molecules. In this talk, we will first delve into our algorithms that design binders […] |
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Fluids confined in nanopores are ubiquitous in nature and technology. In recent years, the interest in confined fluids has grown, driven by research on unconventional hydrocarbon resources -- shale gas and shale oil, much of which are confined in nanopores. When fluids are confined in nanopores, many of their properties differ from those of the […]
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Modern neurotechnologies generate vast and intricate imaging data across multiple modalities, capturing nuanced aspects of brain structure and function in both healthy and diseased states, thus propelling neuroimaging into the 'big data' era. The quantitative analysis of such extensive neuroimaging datasets presents unprecedented opportunities for uncovering novel insights into various neuroscience problems. Machine learning and […] |
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*This seminar will be held in-person in Levine 307 as well as virtually via Zoom. ABSTRACT Medical education traditionally employs the apprenticeship model, where trainees learn directly under the supervision of experienced practitioners. This model necessitates close follow-up and typically provides extremely subjective and non- standardized feedback. Over the years, efforts to introduce more objective […] |
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Materials and chemicals impact daily life, as they enable modern healthcare, preservation of food, and delivering performance and efficiency of transportation and infrastructure. The talk will focus on Dow’s vision and path for carbon neutrality. An overview of Dow Chemical’s portfolio and the breadth of chemistries being practiced will be discussed. Dow has a vision […] |
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Structural materials that are damage-tolerant, lightweight, multifunctional, and sustainable are highly desirable for many engineering applications. Such combinations of properties are often found in the biological world. Organisms from nature construct various biological structural materials for protection, predation, body support, camouflage, etc. Despite the fact that these materials are made from limited constituent materials with […] |
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This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT Despite recent advances in machine learning for robotics, current approaches often lack sample efficiency, posing a significant challenge due to the enormous time consumption to collect real-robot data. In this talk, I will present our innovative methods […]
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Abstract: Biological systems utilize networks of biochemical reactions to drive autonomous and dynamic processes. Examples include the dynamic polymerization of microtubules and the dynamic min protein system in E. Coli. In contrast, synthetic soft and colloidal matter generally requires active stimulation to undergo reconfiguration, such as application of external fields or manual changes in solution […] |
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My group is developing a roadmap for soft actuating materials to replace bulky electric motors in miniature robots requiring large mechanical work output. First, I will describe the materials microstructure and mechanics of polymeric coiled muscles made by twisting nylon fishing lines, and how these actuators use internal strain energy to achieve a “record breaking” performance. Then I […] |
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This will be an in-person event only with in-person attendance in Wu and Chen. This seminar will not be recorded or available on Zoom. Amazon Robotics Tech Talk & Networking Event Amazon Robotics’ Scanless Technologies Team is excited to invite you to join us for a Tech Talk presentation followed by a Networking Event on Friday, 9/20 starting at 10:30am in Wu & Chen […] |
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Discoveries of unique adhesive and frictional properties in biological attachment systems have, over the past two decades, demonstrated how near-surface architecture at lengths between the molecular (a few nm) and continuum (mm) scales can be used to achieve interesting and unique surface mechanical properties. This has spurred considerable research activity in design of meso-scale, near-surface […] |
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This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT Locomotion in complex environments (e.g., rubble, leaf litter, granular media) is essential to mobile engineered systems such as robots. Effective locomotion requires complex control strategies to interact with terrain heterogeneity. Computational intelligence (CI), which typically includes rapid […]
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Bio & Abstract: Jennifer Cochran is the Macovski Professor of Bioengineering and Senior Associate Vice Provost for Research at Stanford University. Prof. Cochran was recruited in 2005 as one of the founding faculty members in Stanford’s Bioengineering department and served as its Chair from 2017-2022. She is also a member of the chemical engineering, immunology, […] |
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Light-matter interactions form the fundamental basis for numerous phenomena and processes in optical devices. This talk will cover ultra-high-quality (Q) whispering-gallery-mode (WGM) optical microresonators which have an unprecedented capability to trap light in a highly confined volume smaller than a strand of human hair. Light-matter interactions are significantly enhanced in high-quality WGM resonators, creating the […] |
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The U.S. Department of Energy’s Energy Earthshots Initiative aims to accelerate breakthroughs of more abundant, affordable and reliable clean energy solutions, to tackle the toughest remaining barriers to addressing the climate crisis and achieving net-zero carbon emissions by 2050. Specifically, the Hydrogen Energy Shot seeks to reduce the cost of clean hydrogen by 80% in […] |
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This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT In this talk, I will discuss how we engineered the foundation of the drone show industry, creating a new form of entertainment that rivals traditional fireworks. Our journey began at Pennovation, where we designed and tested our […]
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Abstract: One of the main challenges in the molecular sciences is identifying promising candidates for a target application given the virtually limitless number of possibilities. Computer simulations and machine learning (ML) are integral tools to survey the vast molecular landscape and the thermodynamic conditions to evaluate their performance. Broadly, a typical pipeline for molecular characterization, […] |
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