This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. This week's speaker will be virtual. ABSTRACT Autonomous flying robots have become widespread in recent years, yet their capability to interact with the environment. remains limited. Moving in multiple fluids is one of the great challenges of mobile […]
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Abstract: In modern engineering, sustainability is a crucial aspect, especially in chemical and biological process systems. This concept has evolved to encompass a holistic approach, emphasizing not only the use of sustainable resources but also the development of systems that are environmentally friendly, smart, and efficient. Such systems aim to minimize waste and optimize resource […] |
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The brain is a powerful organ that regulates health and drives intelligence. How can we see more clearly into the working brain to understand it better? High-resolution optical microscopy has long been an ideal tool due to its spatial sub-micron precision and specificity. However, achieving the necessary spatio-temporal scale for further advancing our understanding of […] |
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This is a hybrid event with a VIRTUAL SPEAKER. There will be in-person attendance in Wu and Chen and virtual attendance on Zoom. ABSTRACT This talk will describe progress in developing a universal theory of architectures for complex networks, motivated by and applied to aerospace, process control, internet, cyberphysical, ecosystems, multiscale physics, turbulence, biology, neuroscience, […] |
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This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT Today's machine perception systems rely extensively on supervision provided by humans, such as natural language. I will talk about our efforts to make systems that, instead, learn from two ubiquitous sources of unlabeled sensory data: visual motion […]
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Abstract Invasive biopsy is the gold standard for diagnosing several diseases; however, these procedures offer a limited, localized view of the disease pathology to the physician and are not risk-free to the patient. Cell-free RNA (cfRNA) in blood plasma reflects dynamic gene expression changes and can facilitate early disease diagnosis, yet current cfRNA assays fall […] |
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Precise RNA expression, tailored to specific brain regions, cell types, and subcellular compartments, is pivotal for orchestrating complex brain functions. In the first part of my talk, I will introduce a confocal imaging-based spatial transcriptomics platform, STARmap, that seamlessly combines in situ hybridization, hydrogel tissue chemistry, and in situ sequencing technologies. Leveraging scalable experimental and computational pipelines, […] |
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This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance on Zoom. ABSTRACT Generative models, which map a latent parameter space to instances in an ambient space, enjoy various applications in 3D Vision and related domains. A standard scheme of these models is probabilistic, which aligns the induced ambient distribution […] |
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Computers can be programmed for superhuman pattern recognition of images and text; however, their application in biology and medicine is still in its infancy. In this talk, I will discuss our advances over the past half-decade, which are accelerating discoveries in the crucial and underinvested area of antibiotic discovery. We developed the first antibiotic designed […] |
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This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT With rapid evolution of sensing, communication, and computation, integrating learning and control presents significant Embodied AI opportunities. However, current decision-making frameworks lack comprehensive understanding of the tridirectional relationship among communication, learning and control, posing challenges for multi-agent […]
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Abstract The demand for viral vectors is poised to soon exceed current production capacities, driven by the surging number of clinical trials for gene and cell therapies. Unfortunately, current manufacturing processes for viral vectors have high costs and low titers. This talk will demonstrate how process systems engineering tools can be leveraged for addressing the […] |
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This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance on Zoom. ABSTRACT With the recent advances in sensing, actuation, computation, and communication, the deployment of large numbers of robots is becoming a promising avenue to enable or speed up complex tasks in areas such as manufacturing, last-mile delivery, search-and-rescue, […] |
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This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. This week's speaker will be virtual. There will be an extended Q&A/discussion after the seminar from 4:00 PM to 4:30 PM. ABSTRACT Based on the theory of homogeneous spaces we derive \textit{geometrically optimal edge attributes} to be used […]
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Abstract Neuroelectronic interfaces have enabled significant advances in both fundamental neuroscience research and the treatment of neurological disorders. However, current neuroelectronic devices have a clear trade-off between invasiveness and spatial resolution, and are unable to achieve seamless integration into the nervous system with cell-type specificity. In this talk, I will first introduce an ultra-small and […] |
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In this seminar, I explore the pivotal role of tissue stem cells and their microenvironment, known as the niche, in regeneration. With a focus on the endothelial cell niche, my work introduces an innovative in vitro vascularized perfusable model tailored for human tissue explants and organoids. My findings also highlight the crucial contribution of paracrine […] |
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This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance on Zoom. ABSTRACT Magnetic fields offer the possibility of manipulating objects from a distance and are ideal for medical applications, as they penetrate human tissue without inflicting any harm on the patient. Magnetic fields can be harnessed to actuate surgical robots, […] |
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This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. This week's speaker will be virtual. ABSTRACT Various applications for autonomous multi-robot systems, such as disaster response, infrastructure repair, agricultural operations, contaminant cleanup, and wildfire suppression, will require these systems to act as distributed sensors, sources, and manipulators […]
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Abstract DNA-binding proteins (DBPs) play critical roles in biology and biotechnology, and there has been considerable interest in the engineering of DBPs with new functions or altered specificities. While there has been success in reprogramming and the specificity of naturally occurring DBPs using selection methods, the computational design of new DBPs that engage with DNA […] |
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Classical and quantum light sources play a fundamental role in science and technology from quantum computing, to communications, manufacturing, defense, sensing, medicine, or imaging. However, scaling the power of lasers has always come at the cost of single mode operation, a scaling question that has been investigated, without success, since the invention of lasers in […]
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The immune system uses a complex network of interacting cells that work together to regulate tissue physiology, homeostasis, and repair. In muscle, a tightly coordinated network of immunocytes and mesenchymal stromal cells (MSCs) is required for adequate skeletal muscle repair after acute injury or disease. Regulatory T cells (Tregs) are important players in regulating excessive […] |
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This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance on Zoom. This seminar will NOT be recorded. ABSTRACT Modeling 3D objects and scenes creates many challenges, both on the analysis and the synthesis sides. The focus of this talk is the compositional structure of objects (into parts) and of […]
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Learn how to commercialize your research and navigate Penn's innovation ecosystem with Penn Engineering: Entrepreneurship. This is the first part of a series from Penn Engineering’s Entrepreneurship group. Featuring: Andrew Tsourkas, Professor of Bioengineering, Co-Founder, AlphaThera, Inc, Co-Founder, StreamLaunch, Llc and Jeffrey Babin, Professor of Practice and Associate Director of Entrepreneurship at Penn Engineering & […] |
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