BE Seminar: “Programming multicellular interactions and organization using synthetic cell adhesion molecules” (Adam Stevens, UCSF)
Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United StatesCell adhesion molecules (CAMs) are ubiquitous in multicellular organisms and specify precise cellular interactions in processes as diverse as tissue development and immune cell trafficking. We have generated an array of synthetic CAMs by combining orthogonal extracellular interactions with native intracellular domains. Diverse homotypic or heterotypic extracellular binding domains specify the connectivity between cells, while […]