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BE Seminar – “Engineering cell state-specific gene regulation with AI and synthetic biology” (Sebastián Castillo Hair, University of Washington)
BE Seminar – “Engineering cell state-specific gene regulation with AI and synthetic biology” (Sebastián Castillo Hair, University of Washington)
Cells across tissues, developmental stages, and disease conditions adopt distinct intracellular states – epigenomic, transcriptomic, and proteomic profiles – to compartmentalize function in time and space. The ability to write DNA- and RNA-encoded programs that sense and interface with cellular states has transformative potential for biotechnology, for example in designing gene therapies with cell type- […]