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Crosslinked biocompatible polymer networks offer unique potential for biomedical applications that demand high resilience under repetitive load-bearing conditions. However, conventional hydrogels often exhibit poor mechanical strength and irreversible damage under cyclic deformation. To address these challenges, this work presents a class of engineered polymer network designed for enhanced mechanical robustness: cryogel-based double-network (DN) hydrogels. In […] |
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Abstract: Solvated macromolecules such as proteins and polymers undergo conformational changes in response to stimuli such as pressure, temperature, pH, ligand binding, and post-translational modification. These transitions are fundamental to biological function, from cellular signaling to misfolding and aggregation, and are increasingly harnessed in applications such as drug delivery, biosensing, and biomaterials design. Understanding how […]
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Abstract: Micron-scale colloidal particles with short-ranged attractions, e.g., colloids functionalized with single-stranded DNA oligomers, have emerged as a powerful platform for studying colloidal self-assembly phenomena with the long-term goal of identifying routes for metamaterial fabrication. Although these systems have been investigated extensively both experimentally and computationally, the role of ‘real world’ features that may impact […] |
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This defense presents my contributions towards general robotics at the microscopic scale. Namely, through the introduction of fully programmable, autonomous microscopic robots free to explore the microscopic world. The robots complete simple, but essential milestones for microscopic robots. The machines we build are small enough to experience the same physics as their biological counterparts, allowing […] |
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