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MEAM Seminar: “The Multiphysics Stochastic Brain”
August 29, 2023 at 10:00 AM - 11:30 AM
Fuelled in particular by current medical challenges in Traumatic Brain Injury, the field of brain mechanics has progressed tremendously in the last decade. Simulations that required months in development and runtime can now be created from patient specific medical images, meshed and run in a fraction of that time. However, and paradoxically, not only do these new models still lack multiphysics capabilities – in clear contradiction with their ultimate purpose to predict functional alteration – but their high fidelity has also exacerbated a problem that the rough early finite element models were naturally avoiding by design, i.e., the stochasticity of the brain. In this presentation, we first highlight why multiphysics modelling considerations are indeed required to adequately tackle the current challenges of brain engineering research. We then focus on the stochasticity of the brain by proposing a series of new numerical methods built on the finite element method accounting for both the intrinsic stochasticity (i.e., variations of the properties within the brain) and extrinsic stochasticity (i.e., variations between individuals). Relevant applications are given throughout as illustrations.
Antoine Jerusalem
Professor of Mechanical Engineering, Department of Engineering Science, University of Oxford
Professor Antoine Jérusalem graduated in 2004 with a double degree from the Ecole Nationale Supérieure de l’Aéronautique et de l’Espace with a Diplôme d’Ingénieur, and from the Massachusetts Institute of Technology with a Master of Science in Aeronautics and Astronautics. In 2007, he obtained his Ph.D. in Computational Mechanics of Materials from MIT, where he stayed as a Postdoctoral Associate for an additional year. He was the group leader of the Computational Mechanics of Materials Group in Madrid’s Advanced Studies Institute of Materials (IMDEA Materials) from 2008 to 2012, and is currently Professor of Mechanical Engineering in the Department of Engineering Science of the University of Oxford. He is also the codirector of the International Brain Mechanics and Trauma Lab and the coEditor-in-Chief of Brain Multiphysics. His work focuses on theoretical and computational mechanics with a wide range of applications in bio- and industrial materials.