Seminar
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BE Seminar: “Microfluidics and Immuno-Materials for Organs-on-a-Chip”
BE Seminar: “Microfluidics and Immuno-Materials for Organs-on-a-Chip”
This presentation will describe microfluidic technologies to conveniently produce life-like pulsatile flows along with applications to study of lung injury, enhancement of in vitro fertilization, and analysis of frequency-dependent cellular responses. The microfluidic technologies range from adaptation of piezo-electric actuator arrays from Braille displays to design of microfluidic circuits that can be designed to switch […]
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MEAM Seminar: “Force, Shape, and Motion in Collective Cell Migration”
MEAM Seminar: “Force, Shape, and Motion in Collective Cell Migration”
Cells migrate collectively to form tissues, to heal wounds, and, in cancer, to metastasize. During these biological processes, the collective migration exhibits a transition from a solid-like state, wherein cell positions remain fixed, to a fluid-like state, wherein cells flow freely and rearrange their positions with their neighbors. Recent mechanics-based models and experiments have demonstrated […]
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BE Seminar Series: Applied Topology in Biological Systems
BE Seminar Series: Applied Topology in Biological Systems
Though rooted in pure mathematics, algebraic topology has recently enabled novel analysis techniques for biological data. Specifically, the method called persistent homology which employs ideas from topology to characterize the voids in a complex network. In this talk, I will briefly introduce persistent homology and give an overview of how we have recently applied this […]
BE Seminar Series: Synchronization is Robust in a Computational Model of Neuronal Network Dynamics and Injury
BE Seminar Series: Synchronization is Robust in a Computational Model of Neuronal Network Dynamics and Injury
At the macroscale, synchronization between brain regions is believed to be important for memory and attention. Injury, including mild traumatic brain injury, can both increase and decrease synchronization as measured by functional MRI, but these changes are not well understood and are unknown at a smaller spatial scale. Here, we examined how injury affects the […]
BE Seminar Series: Heterogeneous, Multi-Scale and Patient-Speci C Pharmacodynamic Systems Models for Cancer with Clinical Applications
BE Seminar Series: Heterogeneous, Multi-Scale and Patient-Speci C Pharmacodynamic Systems Models for Cancer with Clinical Applications
Abstract: Systems models of key signaling pathways in cancer have been extensively used to understand and explore the mechanisms of action of drugs and growth factors on cancer cell signaling. In general, such models predict the effect of mechanical or chemical stimuli (for e.g. drug dosage) in terms of activity of one or more key […]