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3:00 PM

CBE Seminar: “Evolution of the Conformational-free Energy Landscapes of Proteins”

September 18, 2019 at 3:00 PM - 4:00 PM
Wu and Chen Auditorium (Room 101), Levine Hall, 3330 Walnut Street
Philadelphia, PA 19104 United States
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Abstract: One of the holy grails of drug-design is to obtain high-selectivity binding of a drug to the target protein, an extremely challenging endeavor for proteins that share high sequence and structural similarity. We investigate several systems of high biological importance to elucidate how selectivity emerged during evolution and how it can inform the design […]

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